Results 121 to 130 of about 1,275,847 (309)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
In vitro immunological techniques in fascioliasis
, 1975 Experiments were conducted to examine ways of monitoring immunological responses in sheep to infection with Fasciola hepatica. The enzyme- linked immunosorbent assay (ELISA), the radioimmunoassay, and the agar gel precipitin technique were evaluated using the same somatic fluke antigen, for sensitivity and accuracy in the serodiagnosis of fascioliasis ...
openaire +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Proliferative Effect of Proanthocyanidins on HGF-1 and HPDLF Cells: An In Vitro Study
MedicinaBackground and Objectives: The use of proanthocyanidins (PACNs) alongside standard periodontal treatment procedures can improve periodontal and peri-implant tissue healing.
Evelina Alkimavičienė +4 more
doaj +1 more source
Induction of apoptosis and growth inhibition by silodosin and abiraterone acetate in PC-3 human prostate cancer cells [PDF]
Investigative and Clinical UrologyPurpose: Prostate cancer that progresses despite androgen deprivation therapy, known as metastatic castration-resistant prostate cancer (mCRPC) is notoriously difficult to treat.
Lukman Hakim +3 more
doaj +1 more source
Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention. [PDF]
BioTech (Basel), 2023 de Bardet JC +6 more
europepmc +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
In Vitro Techniques and Measurements of Phage Characteristics That Are Important for Phage Therapy Success. [PDF]
Viruses, 2022 Glonti T, Pirnay JP.
europepmc +1 more source
The Post–endodontic Adhesive Interface: Theoretical Perspectives and Potential Flaws [PDF]
, 2018 Introduction The aim of this review was to analyze the potential of successful bonds of endodontic posts to radicular dentin as well as the limitations of the post–endodontic adhesive interface. Methods The MEDLINE/PubMed and Web of Science electronic
He, Jianing +2 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source