Results 31 to 40 of about 114,769,226 (147)

Dosimetry for 6-[18F]Fluoro-L-DOPA in humans based on in vivo microPET scans and ex vivo tissue distribution in mice [PDF]

, 2012
Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution over time using harvested organs at different times ...
Lemaire, Christian, Warnock, Geoffrey, Libert, Lionel, Plenevaux, Alain, Luxen, André, Phillips, Christophe, Seret, Alain, Bretin, Florian, Bahri, Mohamed Ali   +8 more
core   +1 more source

The clinical application of in vivo dosimetry for gynaecological brachytherapy: A scoping review

Technical Innovations & Patient Support in Radiation Oncology
Brachytherapy is a key treatment for gynaecological malignancies, delivering high doses to the tumour volume whilst sparing nearby normal tissues due to its steep dose gradient.
Amani A. Chowdhury, Steve Bolton, Gerry Lowe, Eliana Vasquez Osorio, William Hamblyn, Peter J Hoskin   +5 more
doaj   +1 more source

Sensitivity of the IRD whole-body counter for in vivo measurements in the case of accidental intakes

Brazilian Journal of Radiation Sciences, 2017
Intakes of radionuclides by humans may occur in the fuel cycle, nuclear medicine, biological research and in TENORM industries and in case of accidents involving workers and the general public.
Bernardo Maranhão Dantas, Eder Augusto de Lucena, Ana Letícia Almeida Dantas   +2 more
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Assessment of a 2D electronic portal imaging devices-based dosimetry algorithm for pretreatment and in-vivo midplane dose verification

Advanced Biomedical Research, 2016
Background: The use of electronic portal imaging devices (EPIDs) is a method for the dosimetric verification of radiotherapy plans, both pretreatment and in vivo.
Ali Jomehzadeh, Parvaneh Shokrani, Mohammad Mohammadi, Alireza Amouheidari   +3 more
doaj   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

In vivo dosimetry in pelvic brachytherapy

, 2022
Brachytherapy is an effective treatment in the curative management of prostate and gynaecological cancers. With advances in technology, brachytherapy has increased in complexity in recent years.
Prise, Kevin M, Workman, Geraldine, Housell, Alan R, Prise, Kevin M; id_orcid, Jain, Suneil, Houlihan, Orla Anne, Hounsell, Alan R   +6 more
core   +1 more source

On the Possibility to Use the Charge Imbalance in Patients Undergoing Radiotherapy: A New Online, In Vivo, Noninvasive Dose Monitoring System

Applied Sciences, 2021
This paper describes a new real-time, in vivo, noninvasive, biasless detector system acting as a beam monitoring and relative dose measurement system.
G A Pablo Cirrone, Nino Amato, Roberto Catalano, Alessandro Di Domenico, Giacomo Cuttone, Pietro Lojacono, Alfio Mazzaglia, Fabrizio Pace, Giuseppe Pittà, Luigi Raffaele, Vincenzo Salamone, Corrado Spatola, Giada Petringa   +12 more
doaj   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Endocavitary in vivo dosimetry for IMRT treatments of gynecologic tumors

, 2011
The accuracy and reproducibility of endometrial carcinoma treatment with intensity-modulated radiotherapy (IMRT) was assessed by means of in vivo dosimetry.
Savino Cilla, Deodato F, Digesù C, Cinzia Digesù, Piermattei, Angelo, Domenico Sabatino, Cilla, Savino, Morganti, Alessio Giuseppe, Gabriella Macchia, Macchia, Gabriella, Francesco Deodato, Digesu', Cinzia, Sabatino, Domenico, Alessio G. Morganti, Piermattei A., Macchia G, Angelo Piermattei, Cilla S, Sabatino D, Deodato, Francesco   +19 more
core   +1 more source