CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Multi-Target Anti-Psoriatic Effects of <i>Melissa officinalis</i>: Phytochemical, Redox, Immunological, and Histological Evidence from an In Vivo Study. [PDF]
Daskalovic B +12 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Modulation of dental caries-associated oxidative stress by different restorative materials: A salivary malondialdehyde-based <i>in vivo study</i>. [PDF]
Meena SS +3 more
europepmc +1 more source
[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
Iodoquinoline-Biofortified Lettuce as a Safe and Bioavailable Dietary Iodine Source: In Vivo Study in Rats. [PDF]
Dyląg A +4 more
europepmc +1 more source
Evaluation of a new implant for Tibial Tuberosity Transposition in dogs: An ex vivo study. [PDF]
Rampanelli G +8 more
europepmc +1 more source
Antimicrobial activity of Nd: YAG irradiation, laser activated photodynamic therapy and passive ultrasonic irrigation on enterococcus faecalis biofilms (an ex vivo study). [PDF]
El Gazar SM +4 more
europepmc +1 more source
In Vivo Study of Intra-articular Tualang Honey Formulation as a Potential Alternative to Synvisc® in an Osteoarthritic Rabbit Model. [PDF]
Nour-El-Huda AR +7 more
europepmc +1 more source

