Results 121 to 130 of about 302,552 (286)

On the defence of responsible human judgement in peer review

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract Peer review is essential for scientific progress. When it works well, it combines expertise, fairness, proportionality, skepticism, generosity, and discretion. When it fails, it becomes a theatre for egotistical display, laziness, coercion, and, lately, reliance on artificial intelligence tools. Editors, reviewers, and authors must join forces
João B. P. Soares, Thomas A. Adams II
wiley   +1 more source

Implementing prescriber-pharmacist collaboration to improve evidence-based medication prescribing using asynchronous, non-interruptive electronic health record notifications

open access: yesImplementation Science
Background Inappropriate prescribing of Direct Oral Anticoagulants (DOACs) is a leading cause of adverse outcomes. Electronic health record (EHR)-based notification strategies may support evidence-based prescribing and reduce adverse events.
Geoffrey D. Barnes   +8 more
doaj   +1 more source

Spotlight commentary: Addressing the persistent problem of benzodiazepine overuse, time for clinical, educational and AI‐driven reform

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Jakša Vukojević   +3 more
wiley   +1 more source

Antipsychotic Drug Interactions and Short‐Term Mortality Risk in People With Dementia: A National Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Antipsychotics are often prescribed in the management of behaviors and psychological symptoms of dementia. While the potential harms of antipsychotic use in people with dementia have been established, little is known about the risk associated with antipsychotic drug–drug interactions (DDIs). This study aims to examine the patterns of antipsychotic DDIs
Edward C.Y. Lau   +7 more
wiley   +1 more source

Inappropriate Prescribing in the Elderly

open access: yesJournal of the Royal College of Physicians of London, 1987
K R, Adams   +5 more
openaire   +2 more sources

Operationalizing Precision Medicine in Drug Development: Predictive Biomarkers, Companion Diagnostics, and Regulatory Pathways

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Precision medicine offers the opportunity to improve the benefit–risk profile of new therapies by prospectively identifying patients most likely to respond or least likely to experience harm; however, its systematic integration into drug development remains inconsistent outside oncology.
Ingrid Holst‐Laubjerg   +1 more
wiley   +1 more source

Assessment tool for potentially inappropriate medication use in the elderly: a scoping review protocol

open access: yesRevista de Ciências Farmacêuticas Básica e Aplicada, 2020
Potentially Inappropriate Medication for the elderly (PIM) are drugs in which the safety risks may exceed the benefits, especially when there are safer alternatives.
Geovana Schiavo   +3 more
doaj  

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian   +5 more
wiley   +1 more source

It takes a village: decreasing inappropriate antibiotic prescribing for upper respiratory tract infections

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Objective: Prescribing of antibiotics for viral upper respiratory infections (URIs) remains a pressing public health problem. We sought to reduce inappropriate prescribing of antibiotics for URIs in Mayo Clinic Arizona.
Jamilah L. Shubeilat   +3 more
doaj   +1 more source

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