Results 81 to 90 of about 302,552 (286)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Determinants of appropriate antibiotic and NSAID prescribing in unscheduled outpatient settings in the veterans health administration

BMC Health Services Research
Background Despite efforts to enhance the quality of medication prescribing in outpatient settings, potentially inappropriate prescribing remains common, particularly in unscheduled settings where patients can present with infectious and pain-related ...
Michael J. Ward, Michael E. Matheny, Melissa D. Rubenstein, Kemberlee Bonnet, Chloe Dagostino, David G. Schlundt, Shilo Anders, Thomas Reese, Amanda S. Mixon   +8 more
doaj   +1 more source

Impact of Stewardship Reimplementation on Inappropriate Antibiotic Prescribing for Acute Respiratory Infections in Urgent Care

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Sustaining reductions in inappropriate antibiotic prescribing for acute respiratory tract infections (ARTIs) remains challenging, with improvements often diminishing after stewardship interventions end.
Theresa Ubano Perez, Leslie Ann Loza-Zamora, Russel Grant, Massoud Dezfuli   +3 more
doaj   +1 more source

Inappropriate prescribing in the hospitalized elderly patient: Defining the problem, evaluation tools, and possible solutions

, 2010
Robert L Page II1, Sunny A Linnebur2, Lucinda L Bryant3, J Mark Ruscin41Associate Professor of Clinical Pharmacy and Physical Medicine, Clinical Specialist, Division of Cardiology and Heart Transplantation, 2Associate Professor of Clinical Pharmacy ...
Lucinda L Bryant, Robert L Page II, Sunny A Linnebur, et al   +3 more
core  

Inappropriate prescribing in elderly people with diabetes admitted to hospital

, 2016
Inappropriate prescribing; Elderly people; DiabetesPrescripción inadecuada; Ancianos; DiabetesPrescripció inadequada; Persones grans; DiabetisAims To assess inappropriate prescribing in older people with diabetes mellitus during the month prior to a ...
San-José, Antonio, Formiga, Francesc, Vidal, Xavier, Chivite, David, Barbé Gil-Ortega, José, Rosón Hernández, Beatriz, Agustí, Antònia   +6 more
core   +1 more source

Safety concerns reported by coroners following fentanyl patch fatalities in England, Wales and Northern Ireland between 1997 and 2024

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To identify safety concerns reported by coroners following fentanyl patch‐related deaths in England, Wales and Northern Ireland, and determine differences in coronial reporting. Methods A systematic case series linking the National Programme on Substance Use Mortality (NPSUM) and the Preventable Deaths Tracker (PDT) (https ...
Eman Mshari, Caroline S. Copeland, Georgia C. Richards   +2 more
wiley   +1 more source

Factors influencing inappropriate antibiotic prescription in respiratory tract infections in general practice

Scientific Reports
Respiratory tract infections (RTIs) are common in general practice, and represent the main cause of inappropriate antibiotic prescribing, contributing to antimicrobial resistance.
Léa Charton, François Séverac, Yves Hansmann, Juliette Chambe   +3 more
doaj   +1 more source

Inappropriate prescribing of antithrombotic therapy in Ethiopian elderly population using updated 2015 STOPP/START criteria: a cross-sectional study

, 2016
Henok Getachew, Akshaya Srikanth Bhagavathula, Tamrat Befekadu Abebe, Sewunet Admasu Belachew Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Background: Inappropriate
Getachew H, Belachew SA, Bhagavathula AS, Abebe TB   +3 more
core  

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, EarlyView.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Acceptability of Interventions to Address Polypharmacy in Older Adult Outpatients: A Systematic Review and Meta‐Analysis

Health Science Reports
Background and Aims Interventions to address potentially inappropriate prescribing (PIP), where risks outweigh benefits, are effective but often not implemented due to barriers (e.g., patient, provider, systems).
Nav Persaud, Amal Rizvi, Aine Workentin, Becky Skidmore, Emily G. McDonald   +4 more
doaj   +1 more source