Results 41 to 50 of about 10,414 (202)

Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx [PDF]

open access: yes, 2008
A healthy vascular endothelium is coated by the endothelial glycocalyx. Its main constituents are transmembrane syndecans and bound heparan sulphates. This structure maintains the physiological endothelial permeability barrier and prevents leukocyte and ...
Becker, Bernhard F.   +6 more
core   +1 more source

Descripción para el registro de la nueva variedad de poroto tipo navy bean TUC 150 desarrollada por la Estación Experimental Agroindustrial Obispo Colombres [PDF]

open access: yesRevista Industrial y Agrícola de Tucumán, 2018
El proyecto Legumbres Secas de la Estación Experimental Agroindustrial Obispo Colombres ha desarrollado una nueva variedad de poroto (Phaseolus vulgaris L.), blanco chico tipo navy bean, TUC 150.
Oscar N. Vizgarra   +4 more
doaj  

p38MAPK induces apoptosis of glioma cell [PDF]

open access: yes, 2001
目的 研究 p38MAPK基因转染大鼠胶质瘤细胞系C6后对其生物学特性的影响 .方法 利用脂质体介导法将p38MAPK基因导入大鼠胶质瘤细胞系 C6中 ,用免疫细胞化学染色检测其在细胞转染前后的表达情况 ,用 HE染色、流式细胞仪等方法研究其对细胞形态、粘着状况和生长周期的影响 .结果 转染 p CMV5 - p38MAPK质粒组 p38MAPK蛋白表达阳性 ,细胞形态发生变化 ,贴壁性降低 ,出现大量凋亡细胞 .结论 转染 ...
叶菁(第四军医大学西京医院病理科)   +6 more
core   +3 more sources

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth [PDF]

open access: yesNature Medicine, 2016
Cancer cells experience higher oxidative stress from reactive oxygen species (ROS) than do non-malignant cells because of genetic alterations and abnormal growth; as a result, maintenance of the antioxidant glutathione (GSH) is essential for their survival and proliferation.
Shira L, Cramer   +15 more
openaire   +2 more sources

Gastroesphageal Variceal Hemorrhage Induced by Metastatic Liver Tumor of Lung Cancer

open access: yesCase Reports in Oncology, 2012
Gastroesophageal variceal hemorrhage is a lethal complication of portal hypertension. Liver cirrhosis is often the principal cause of the portal hypertensive state. Malignant tumors coexist with portal hypertension in some cases.
Takayuki Honda   +5 more
doaj   +1 more source

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis [PDF]

open access: yes, 2017
Environmental nutrient levels impact cancer cell metabolism, resulting in context-dependent gene essentiality. Here, using loss-of-function screening based on RNA interference, we show that environmental oxygen levels are a major driver of differential ...
Adams, Sylvia   +8 more
core   +1 more source

La inasible experiencia de la Modernidad

open access: yesTópicos. Revista de Filosofía de Santa Fe, 2018
Nuestro objetivo en el presente trabajo es enfatizar las tensiones que existen entre el uso de los conceptos de ironía y ensayo, que hace Lukács en El Alma y las formas, y el modo en que tales conceptos son empleados por Friedrich Schlegel, a fines del siglo XVIII.
openaire   +3 more sources

Una sociedad inasible. La inestable constitución de lo social en el pensamiento de Claude Lefort

open access: yesOXÍMORA Revista Internacional de Ética y Política, 2021
Este trabajo pretende definir conceptos y esquematizar ideas provenientes de la filosofía política de Claude Lefort para pensar las relaciones de los “hombres” con sus formas y condiciones de existencia políticas. En primer lugar me referiré a los rasgos generales de la filosofía de Lefort y luego avanzaré sobre tres conjuntos de conceptos ...
openaire   +3 more sources

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

open access: yesAdvanced Science, Volume 12, Issue 35, September 18, 2025.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu   +20 more
wiley   +1 more source

GelMA/AgNWs Hydrogel Combined with Electrical Stimulation Effectively Promotes Skin Wound Healing

open access: yesAdvanced Materials Interfaces, Volume 12, Issue 14, July 25, 2025.
The doped AgNWs in GelMA hydrogel prevent the wound from being infected and introduce the electrical field into the wound region. COMSOL simulation guides the introduced electric field to be conducive to promoting cell migration and proliferation. Thus, the GelMA/AgNWs hydrogel combined with ES effectively accelerated the healing process of skin wounds.
Xiaoxuan Hou   +6 more
wiley   +1 more source

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