Results 111 to 120 of about 2,744,295 (327)
Models of Innate Neural Attractors and Their Applications for Neural Information Processing [PDF]
arXiv, 2015 In this work we reveal and explore a new class of attractor neural networks, based on inborn connections provided by model molecular markers, the molecular marker based attractor neural networks (MMBANN). We have explored conditions for the existence of attractor states, critical relations between their parameters and the spectrum of single neuron ...
arxiv
A system-wide network reconstruction of gene regulation and metabolism in Escherichia coli [PDF]
, 2018 Genome-scale metabolic models have become a fundamental tool for examining metabolic principles. However, metabolism is not solely characterized by the underlying biochemical reactions and catalyzing enzymes, but also affected by regulatory events. Since the pioneering work of Covert and co-workers as well as Shlomi and co-workers it is debated, how ...
arxiv +1 more source
Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke +2 more
wiley +1 more source
Enzyme economy and metabolic control [PDF]
arXiv, 2014 The metabolic state of a cell, comprising fluxes, metabolite concentrations and enzyme levels, is shaped by a compromise between metabolic benefit and enzyme cost. This hypothesis and its consequences can be studied by computational models and using a theory of metabolic value.
arxiv
Antithrombin: Deficiency, Diversity, and the Future of Diagnostics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Our healthcare system provides reactive sick‐care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which is not sustainable.
Mirjam Kruijt +2 more
wiley +1 more source
Biochemistry and Molecular Biology PBL Cases
MedEdPORTAL, 2006 This resource is a collection of six problem-based learning (PBL) cases suitable for a biochemistry and molecular biology course taken by first- or second-year medical students.
Marshall Anderson
doaj +1 more source
Prenatal Diagnosis, EarlyView.ABSTRACT This manuscript summarises the debate held at the 2024 annual meeting of The International Society for Prenatal Diagnosis (ISPD). Experts discussed whether all fetuses undergoing fetal therapy should undergo exome sequencing. Arguments in favor included that, with increasing experience and better clinical availability, exome sequencing can ...
Teresa N. Sparks +2 more
wiley +1 more source
Vaccination strategies for people living with inborn errors of metabolism in Brazil
Jornal de Pediatria, 2023 Objective: Through a literature review, make recommendations regarding immunizations in people living with Inborn Error of Metabolism (IEM) in Brazil, assess the possible impact on metabolic decompensations after immunization, and if this specific ...
Barbara C.F. Ramos +6 more
doaj
Prenatal Diagnosis, EarlyView.ABSTRACT Objective The aim of this study was to compare placenta‐related complications (adverse placental syndrome) between different types of fetal CHD based on cardiac hemodynamics. Method All CHD cases diagnosed prenatally by fetal ECHO during 2009–2023 were selected.
Maartje C. Snoep +10 more
wiley +1 more source
Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings
Pediatric Discovery, EarlyView.Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong +13 more
wiley +1 more source