Results 291 to 300 of about 38,522 (353)

Glycine N‐Acyltransferase Deficiency due to a Homozygous Nonsense Variant in the GLYAT: A Novel Inborn Error of Metabolism

JIMD Reports, Volume 66, Issue 5, September 2025.
ABSTRACT The enzyme glycine N‐acyltransferase (GLYAT) plays a crucial role in detoxifying both xenobiotic and endogenous compounds that contain a carboxylic acid group, such as benzoic acid. Data on the impact of human GLYAT on the glycine conjugation pathway is limited and difficult to determine.
Mona Nourbakhsh, Mohammad Miryounesi, Ali Tale, Parvaneh Karimzadeh, Hossein Sadeghi, Mohammad‐Reza Ghasemi, Nasrin Alipour, Elham Pourbakhtyaran, Nakisa Hooman, Maryam Razzaghy‐Azar, Mitra Nourbakhsh, Lil Klaas, Daniel Schulke, Jörn Oliver Sass   +13 more
wiley   +1 more source

The Intergenerational Impact of Maternal Childhood Adversity on Child Behavior and Neurodevelopment: The Healthy MiNDS Protocol

International Journal of Methods in Psychiatric Research, Volume 34, Issue 3, September 2025.
ABSTRACT Objectives Here we present Healthy MiNDS, a cohort of mothers and their newborns in São Paulo, Brazil, designed to investigate how maternal adverse childhood experiences (ACEs) intergenerationally affect child behavior and neurodevelopment, while exploring underlying biological mechanisms. Methods The study included seven encounters, beginning
Danilo Micali, Ana Carolina Coelho Milani, Camilla Salmeron, Célia Araújo, Aline Camargo Ramos, Marcos Roberto Fanton, Sara B. VanBronkhorst, Nitamar Abdala, Ivaldo Silva, Sintia Iole Belangero, Cristiane S. Duarte, Jonathan Posner, Andrea Parolin Jackowski   +12 more
wiley   +1 more source

Harnessing Next-Generation Sequencing as a Timely and Accurate Second-Tier Screening Test for Newborn Screening of Inborn Errors of Metabolism. [PDF]

Int J Neonatal Screen
Chan TCH, Mak CM, Yeung MCW, Law EC, Cheung J, Wong TK, Cheng VW, Lee JKH, Wong JCL, Fung CW, Belaramani KM, Kwok AMK, Tsang KY.   +12 more
europepmc   +1 more source

Physical activity during pregnancy stratified by body mass index: A focus on class 3 obesity

Pregnancy, Volume 1, Issue 5, September 2025.
Abstract Introduction The prevalence of pre‐pregnancy obesity, including pre‐pregnancy class 3 obesity, has increased over time, with significant implications for maternal and neonatal well‐being. Regular physical activity may mitigate these risks.
Eliza M. Nguyen, Megan E. Branda, Linda M. Szymanski   +2 more
wiley   +1 more source

Trait mapping differentiates loci influencing spike and flag leaf glaucousness in wheat

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract The bluish‐white appearance of some plants, known as glaucousness, results from the scattering effect of visible light due to plant surface waxes. This adaptive trait can contribute to tolerance of abiotic stresses in wheat (Triticum aestivum L.) such as drought, solar radiation, and heat.
Daniela Miller, Luis Rivera‐Burgos, Mohammed Guedira, Noah DeWitt, Brian Ward, J. Paul Murphy, Amanda M. Hulse‐Kemp, Gina Brown‐Guedira   +7 more
wiley   +1 more source

Systematic Multi‐Trait Study of Genetic Correlation and Causality Relationships Between General Medical Conditions and Mental Disorders

Acta Psychiatrica Scandinavica, Volume 152, Issue 3, Page 236-249, September 2025.
ABSTRACT Introduction Increasing evidence has highlighted bidirectional associations between mental disorders and general medical conditions, with underlying causes ranging from lifestyle habits and side effects from medications to genetic contributions. Novel methods now provide a way to estimate the shared genetic underpinnings and the possibility of
Ron Nudel, Maria Da Re, Michael E. Benros   +2 more
wiley   +1 more source