Results 121 to 130 of about 781 (234)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim   +4 more
wiley   +1 more source

From Molecules to Machines: An Integrative Framework Linking Molecular Pathogenesis, Multi‐Factorial Risk, Risk Stratification, Clinical Management, and Artificial Intelligence in QT Prolongation and Sudden Cardiac Death

open access: yesClinical Cardiology, Volume 49, Issue 6, June 2026.
An integrative conceptual framework linking the five principal domains addressed in this review. Beginning at the molecular level, loss‐of‐function mutations in KCNQ1 and KCNH2 reduce outward repolarizing currents (IKs and IKr), while gain‐of‐function SCN5A mutations augment late inward sodium current (INa), establishing the genetic substrate for ...
Mojtaba Farjam   +2 more
wiley   +1 more source

Perioperative Piperacillin/Tazobactam Reduces Early Onset SSI in Preirradiated Patients Undergoing Microvascular Head and Neck Reconstruction

open access: yesHead &Neck, Volume 48, Issue 6, Page 1519-1528, June 2026.
ABSTRACT Background Preirradiated patients undergoing microvascular head and neck reconstruction for tumor recurrence or osteoradionecrosis (ORN) face surgical site infection (SSI) rates exceeding 30%. The impact of perioperative extended‐spectrum antibiotic coverage remains unclear. This study hypothesizes that calculated prophylaxis with piperacillin/
Johannes G. Schuderer   +11 more
wiley   +1 more source

Uncovering the key bilateral trade linkages in the U.S. domestic food supply chain through disruption simulations

open access: yesJournal of the Agricultural and Applied Economics Association, Volume 5, Issue 2, Page 154-179, June 2026.
Abstract This paper uses counterfactual simulations to examine the impact of bilateral trade linkage disruptions on the U.S. agricultural and food trade system. Using an econometric gravity model, we estimate the relationship between disruptions and trade flows, identify critical state‐to‐state trade linkages whose disruption would significantly impact
Taejun Mo, Sandy Dall'erba
wiley   +1 more source

A value chain analysis of digitalizing hospital-at-home services in Finland. [PDF]

open access: yesHealth Care Manage Rev
Wang F   +6 more
europepmc   +1 more source

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