Results 181 to 190 of about 861,250 (295)

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

Effect of Sex, Anesthesia Method, Physiological Asymmetry, and Strain on Rat Lymphatic Vessel Contractility Assessed via Near-Infrared Spectroscopy and Linear Mixed-Effects Modeling. [PDF]

Microcirculation
Mavris S, Chin R, Hsu SY, Gleason RL, Dixon JB, Nepiyushchikh Z.   +5 more
europepmc   +1 more source

Mitochondrial haplotype and sex modulate responses to endurance exercise training

The Journal of Physiology, EarlyView.
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn, Tianhao Wei, Ryan Pettit‐Mee, Eunyoung Kim, Robert V. Musci, Jonathan Wanagat, Hoang Van M. Nguyen, Arlan Richardson, Hyunyoung Kim   +8 more
wiley   +1 more source

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

The Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana, Collin Matsumoto, L. Fernando Santana   +2 more
wiley   +1 more source

Morphine and nicotine intake in high drinking in the dark mice is reduced by informatics-nominated and translationally relevant compounds. [PDF]

Front Psychiatry
Ginder DE, Palacios J, Stewart M, Jensen BE, Borrego MB, Tzab L, Ozburn AR.   +6 more
europepmc   +1 more source

Advances in the Integration of Genomic and Phenomic Tools in Cowpea Breeding for Improving Stress Resilience and Grain Yield and Quality

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Cowpea (Vigna unguiculata L. Walp) is a multi‐use crop highly valued as a food crop, high‐protein fodder, and sustainable cover crop. Yet, it remains underused, and yields in most growing regions are below the crop's potential due to multiple biotic and abiotic stresses.
Habib Akinmade, Luis Getino, María Muñoz‐Amatriaín, Esteban Rios   +3 more
wiley   +1 more source

CSF1R-related leukoencephalopathy: experimental models and potential for treatment. [PDF]

Dis Model Mech
Hume DA, Irvine KM.
europepmc   +1 more source

Balancing Short‐Term Genetic Gain and Long‐Term Diversity: Haplotype‐Based Breeding Strategies for Yield Improvement in Chickpea

Legume Science, Volume 8, Issue 4, December 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is one of the most important grain legumes and provides a major source of protein, vitamins and minerals worldwide. Despite decades of traditional breeding delivering significant genetic gains in disease resistance and adaptation, seed yield improvement has advanced only incrementally, constrained by the highly ...
Bhargava Kotte, Rutwik Barmukh, Will Shaffer, Oluwaseun J. Akinlade, Ajaya Karkee, Michael Udvardi, Lee Hickey, Rajeev K. Varshney   +7 more
wiley   +1 more source

MDMA alters fear extinction, and reduces alcohol consumption in inbred alcohol preferring iP rats but not outbred Wistar rats. [PDF]

Neuropsychopharmacology
Huckstep KL, Newton B, Bailey G, Charlton A, Pearl AJ, Maddern XJ, Brown RM, McNally GP, Lubman DI, Arunogiri S, Morley KC, Campbell EJ, Lawrence AJ, Walker LC.   +13 more
europepmc   +1 more source

Root trait dynamics of historical canola varieties under low and high nitrogen supply

The Plant Phenome Journal, Volume 9, Issue 1, December 2026.
Abstract Nitrogen fertilizer is a major input cost in crop production, making it crucial to enhance nitrogen use efficiency (NUE) to reduce fertilizer dependence without compromising yields. Root system architecture (RSA) is a key determinant of nutrient acquisition, particularly under nutrient‐limited conditions.
Shankar Pahari, Raju Soolanayakanahally
wiley   +1 more source