Large-scale behavioral characterization of oxycodone self-administration in heterogeneous stock rats reveals initial analgesic effects are associated with addiction-like behaviors. [PDF]
Kallupi M +34 more
europepmc +1 more source
Antihypertensive effect of acupuncture involve reshaping gut microbiota and alleviating gut inflammation in spontaneously hypertensive rats. [PDF]
Jie Z +10 more
europepmc +1 more source
Clinical and genetic characterization of intellectual disability
This study examines the etiological factors and comorbidities in a large cohort of Finnish patients with intellectual disability. Genetic causes—including chromosomal abnormalities and pathogenic gene variants—were more frequently identified in individuals with moderate to profound intellectual disability.
Aarni Venetvaara +14 more
wiley +1 more source
Comprehensive behavioral profiling in male spontaneously hypertensive rats: latent trait mapping supports a valid multidomain ADHD model. [PDF]
Kim HB +8 more
europepmc +1 more source
This scoping review identifies intervention ingredients that address the F‐words for childhood development in community‐based physical activity programs for children with physical disabilities. An electronic database and hand search of the international literature was conducted.
Belinda Munroe +5 more
wiley +1 more source
PEG-fusion of viable sciatic nerve isografts restores axonal structure and behavioral recovery after segmental-loss sciatic nerve injuries in Lewis rats. [PDF]
Yang CZ +10 more
europepmc +1 more source
Exploratory quantitative analyses suggested that higher seizure severity and COVID‐era enrollment were associated with lower intervention completion, while qualitative findings identified cumulative caregiver burden, medical instability, competing demands, and perceived intervention fit as contributors to attrition.
Carly Hyde Tillis +10 more
wiley +1 more source
Temporal Mapping of CSVD-Related White Matter Lesions and Concurrent Neurovascular Dysfunction in Spontaneously Hypertensive Rats. [PDF]
Peng J +8 more
europepmc +1 more source
ABSTRACT Aims Animal models of prediabetes (Pre‐DM) are essential for studying metabolic disease and testing therapies, yet high‐fat diet (HFD) and HFD‐plus‐streptozotocin (STZ) protocols vary in feeding duration, STZ dose, and diagnostic criteria and rarely account for sex.
Min Xu +7 more
wiley +1 more source
Sex-Dependent Responses in the Retina Proteome to Ocular Hypertension in a Mouse Model of Glaucoma. [PDF]
Zaman K +4 more
europepmc +1 more source

