Results 61 to 70 of about 861,250 (295)

Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]

, 2000
Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Sluyter, Frans, Hogg, Sandy, Hof, Marleen, Steimer, Thierry, de Ruiter, Anne, Würbel, Hanno, Hogg, Sandy,, Sluyter, Frans,, Koolhaas, Jaap, Hof, Maleen,, Koolhaas, Jaap,, Steimer, Thierry,, Würbel, Hanno,, Ruiter, Anne de,   +13 more
core   +1 more source

The Norway rat, from an obnoxious pest to a laboratory pet

eLife, 2020
The laboratory rat was the first mammal domesticated for research purposes. It is descended from wild Norway rats, Rattus norvegicus, which despite their name likely originated in Asia.
Klaudia Modlinska, Wojciech Pisula
doaj   +1 more source

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

Animal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud, Aysar Nashef, Imad Abu‐Elnaaj, Fuad A. Iraqi   +3 more
wiley   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Estimating Growth of Inbred Rats for Behavioral and Biological Study

, 1965
Relative to the control of food deprivation and drug and surgical studies, empirical procedures are described for estimating body weight of individual rats of an inbred strain from approximately 12 through 30 wk. of age.
Michael Kaplan, Eugenie F. Kaplan
core   +1 more source

Identification of the miniature pig inbred line by skin allograft

Journal of Integrative Agriculture, 2015
Skin grafting has been used as one of the most reliable tests to determine the genetic stability of laboratory animal such as mice and rats inbred line, but no identification of swine inbred lines by skin grafting has been reported. At present, Wuzhishan
Yu-lian MU, Lan LIU, Shu-tang FENG, Tian-wen WU, Kui LI, Jun-you LI, Wei HE, Qian GAO, Wen-fang ZHOU, Jing-liang WEI, Fang TANG, Shu-lin YANG, Zhi-gu WU, Ying XIA, Tong-zhu SUN   +14 more
doaj   +1 more source

The mechanism of labor in nonhuman primates: A look inside

The Anatomical Record, EarlyView.
Abstract While in humans, the flexed position of the fetus and its rotating course down the birth canal are well documented, in other primates the mechanism of labor is unknown. Despite the lack of comparative data, it is commonly assumed that the human obstetric mechanism is unique, and anthropologists have disputed when and why the transition to the ...
Melissa K. Stoller
wiley   +1 more source

Avaliação temporal dos efeitos de estresse de contenção no frio sobre os comportamentos relacionados a ansiedade e depressão em duas linhagens de camundongos fêmeas: Swiss e C57BL/6J [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013A resposta de estresse tem valor adaptativo na sobrevivência das espécies, porém quando há uma ...
Marchette, Renata Cristina Nunes
core  

Superovulation with an anti-inhibin monoclonal antibody improves the reproductive performance of rat strains by increasing the pregnancy rate and the litter size

Scientific Reports
Rats are multiparous rodents that have been used extensively in research; however, the low reproductive performance of some rat strains hampers the broader use of rats as a biomedical model.
Keiji Mochida, Kohtaro Morita, Yoshio Sasaoka, Kento Morita, Hitoshi Endo, Ayumi Hasegawa, Masahide Asano, Atsuo Ogura   +7 more
doaj   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source