Results 131 to 140 of about 2,317,355 (365)
Phenotype and gene signature of testicular tumors in 129.MOLF‐Chr19 mice resemble human teratomas
Abstract Background Testicular germ cell tumor (TGCT) is the most common type of tumor in young men. Type II germ cell tumors including postpubertal‐type teratomas are derived from the germ cell neoplasia in situ (GCNIS), whereas prepubertal‐type teratomas arise independently of the GCNIS.
Fabian A. Gayer+4 more
wiley +1 more source
THE OCCURRENCE AND HEREDITARY BEHAVIOR OF TWO NEW DOMINANT MUTATIONS IN AN INBRED STRAIN OF DROSOPHILA MELANOGASTER [PDF]
Margaret C. Mann
openalex +1 more source
Electroconvulsive Thresholds of Inbred Mouse Strains
The electroconvulsive threshold (ECT) test is used commonly in the screening of anti-epileptic drugs in rodent models, but little is known about its genetic or mechanistic basis. Thresholds for minimal clonic, maximal tonic, or psychomotor (partial) seizures were determined in 16 different inbred mouse strains in two different laboratories.
Frankel, W N+4 more
openaire +3 more sources
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa+2 more
wiley +1 more source
Microarrays are designed to measure genome-wide differences in gene expression. In cases where a tissue is not accessible for analysis (e.g. human brain), it is of interest to determine whether a second, accessible tissue could be used as a surrogate for
Matthew N Davies+5 more
doaj +1 more source
Abstract Aim A study reported that therapeutic hypothermia (TH) did not reduce the combined prognosis of mortality and disability at 18 months, in low‐ and middle‐income countries for patients with hypoxic ischaemic encephalopathy (HIE) who received TH, suggesting its no implementation in these regions.
Carlos Fajardo+7 more
wiley +1 more source
The Effect of Methylcholanthrene on the Incidence of Lung Tumours in Two Inbred Strains of Mice and their Reciprocal Hybrids [PDF]
E. W. Miller, F. C. Pybus
openalex +1 more source
ABSTRACT Antipsychotic drugs (APDs) are a diverse class of neuroactive pharmaceuticals increasingly detected in surface and ground waters globally. Some APDs are classified as posing a high environmental risk, due, in part, to their tendency to bioaccumulate in wildlife, including fish.
Gabrielle Wasser‐Bennett+4 more
wiley +1 more source
Our Translational Loop integrates patient genetic data with Drosophila models to study disease mechanisms. We identified ACO2 variants in a patient linked to ICRD and show that our animal model mirrors key aspects of the disease. These insights help pinpoint therapeutic targets, advancing research toward treatments for rare genetic disorders.
Edgar Buhl+15 more
wiley +1 more source
THE RESULTS OF CROSSES BETWEEN INBRED STRAINS OF GUINEA PIGS, DIFFERING IN NUMBER OF DIGITS [PDF]
Sewall Wright
openalex +1 more source