Results 81 to 90 of about 2,317,355 (365)
Differences in Exercise Capacity and Responses to Training in 24 Inbred Mouse Strains
Frontiers in Physiology, 2017 Changes in cardiorespiratory fitness in response to a standardized exercise training protocol differ substantially between individuals. Results from cross-sectional, twin, and family studies indicate genetics contribute to individual differences in both ...
Joshua J. Avila +2 more
doaj +1 more source
Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]
, 2009 We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R +8 more
core +1 more source
ESC Heart Failure, EarlyView.Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti +14 more
wiley +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 1991 The immunomodulatory effect of cimetidine (CIM), a histamine type-2 receptor antagonist, was evaluated in respect to the blastogenic response to Con A of Wistar Furth (WF) rats infected by the Y strain of Trypanosoma cruzi (T. cruzi).
M.N. Sato +5 more
doaj +1 more source
Scientific Reports, 2021 Circadian variability is driven by genetics and Diversity Outbred (DO) mice is a powerful tool for examining the genetics of complex traits because their high genetic and phenotypic diversity compared to conventional mouse crosses.
Sam-Moon Kim +7 more
doaj +1 more source
Establishment and characterization of the Komeda diabetes-prone rat as a segregating inbred strain.
Experimental animals, 2003 The Komeda diabetes-prone (KDP) rat is a spontaneous animal model of human autoimmune type 1 diabetes. By positional cloning of the non-MHC major susceptibility locus lddm/kdp1, we recently identified a nonsense mutation in Cblb and also found that ...
N. Yokoi +6 more
semanticscholar +1 more source
Genetic basis of voluntary water consumption in two divergently selected strains of inbred mice
Veterinary Medicine and Science, 2019 Background Inbred mouse strains with normal renal function show a substantial difference in daily water consumption across strains. This study uses two strains of inbred mice C57BR/CDJ (BR), which are high consumers, and C57BL/10J (BL), which are low ...
Maria Haag +2 more
doaj +1 more source
Microsatellite Marker Analysis for Laboratory Mice Profiling
Advanced Biomedical Research, 2019 Background: The key point in the production procedure of inbred animals is checking the genetic purity. Skin grafting and coat color test are used traditionally to prove genetic purity, but they have some disadvantages.
Reza Ahangari Cohan +4 more
doaj +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Epilepsia Open, EarlyView.Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza +4 more
wiley +1 more source