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A Spectral Theory for Wright’s Inbreeding Coefficients and Related Quantities [PDF]
PLOS Genetics, 2020 Abstract Wright’s inbreeding coefficient, F ST , is a fundamental measure in population genetics. Assuming a predefined population subdivision, this statistic is classically used to evaluate population structure at a given genomic locus. With large numbers of loci,
Olivier François, Clément Gain
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Estimation of inbreeding effect on conception in Czech Holstein
Czech Journal of Animal Science, 2019 The influence of calculated inbreeding coefficients on the conception of heifers and cows was analysed by a two-trait binary model for conceived/not conceived after each insemination on 677 234 Czech Holstein cows and heifers with 3 248 299 insemination ...
Michala Hofmannová +3 more
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Simultaneous Estimation of Null Alleles and Inbreeding Coefficients [PDF]
Journal of Heredity, 2008 Although microsatellites are a very efficient tool for many population genetics applications, they may occasionally produce "null" alleles, which, when present in high proportion, may affect estimates of key parameters such as inbreeding and relatedness coefficients or measures of genetic differentiation.
Igor J, Chybicki, Jaroslaw, Burczyk
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Advanced Science, EarlyView.A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
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The role of inbreeding in the extinction of a European royal dynasty. [PDF]
PLoS ONE, 2009 The kings of the Spanish Habsburg dynasty (1516-1700) frequently married close relatives in such a way that uncle-niece, first cousins and other consanguineous unions were prevalent in that dynasty.
Gonzalo Alvarez +2 more
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EXACT INBREEDING COEFFICIENTS IN POPULATIONS WITH OVERLAPPING GENERATIONS [PDF]
Genetics, 1978 ABSTRACT A theory is given that allows inbreeding coefficients to be calculated exactly for populations with overlapping generations. Emphasis is placed on providing equations well suited for computer iteration. Both monoecious and dioecious populations are considered and family size is not restricted to being Poisson.
S C, Choy, B S, Weir
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Advanced Science, EarlyView.A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
The effect of inbreeding on the growth ability of meat sheep breeds in the Czech Republic
Czech Journal of Animal Science, 2021 The aim of this study was to present the trend of inbreeding and to estimate the effect of inbreeding on the growth ability of lambs in the three most common sire breeds in the Czech Republic: Suffolk (SF; n = 49 345), Charollais (CH; n = 14 189) and ...
Michaela Černá +2 more
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Coefficients of Inbreeding and Relationship [PDF]
The American Naturalist, 1922 n ...
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Revised Calculation of Kalinowski’s Ancestral and New Inbreeding Coefficients [PDF]
Diversity, 2020 To test for the presence of purging in populations, the classical pedigree-based inbreeding coefficient (F) can be decomposed into Kalinowski’s ancestral (FANC) and new (FNEW) inbreeding coefficients. The FANC and FNEW can be calculated by a stochastic approach known as gene dropping.
Harmen P. Doekes +5 more
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