Results 101 to 110 of about 25,739 (228)

NEOPLASIA DE CÉLULAS DENDRÍTICAS BLÁSTICAS PLASMOCITÓIDES COM ACOMETIMENTO OCULAR: RELATO DE DOIS CASOS

Hematology, Transfusion and Cell Therapy
Introdução: A neoplasia de células dendríticas blásticas plasmocitóides (NCDBP) é rara, seus principais locais de envolvimento são a pele e medula óssea, com frequente envolvimento do sistema nervoso central (SNC).
COC Vieira, Y Gonzaga, C Mattosinho, LVD Valle, SH Nunes, S Garcia, CB Burrowes, RP Souza, TS Gregório, LAO Ananias   +9 more
doaj   +1 more source

Syntaxin 12 Sustains Endosomal‐Lysosomal Homeostasis and Survival in Glioblastoma Stem‐Like Cells

Traffic, Volume 27, Issue 3, September 2026.
Syntaxin12 maintains endolysosomal trafficking and lysosomal homeostasis in glioblastoma cells. Syntaxin12 depletion disrupts lysosomal organization, impairs endolysosomal progression and mTOR‐lysosome communication, and compromises adaptive pathways required for cell survival. ABSTRACT Glioblastoma cells display a striking vulnerability to disruptions
Clément Maghe, Agnieszka Barbach, Gwennan André‐Grégoire, Clotilde C. N. Renaud, Margaux Le Guyon, Rosalie Moreau, Nicolas Bidère, Julie Gavard   +7 more
wiley   +1 more source

Magnetic Field Disturbance Induced by the Enhanced Suprathermal Ring Current in the Magnetosphere of Saturn

Geophysical Research Letters, Volume 53, Issue 15, 16 August 2026.
Abstract Saturn's ring current, which modulates the global magnetic field configuration, varies dynamically with hot plasma injections. However, quantifying transient magnetic field disturbances remains challenging in the absence of in situ measurements on Saturn's surface.
Yimeng Li, Chao Yue, Yongfu Wang, Konstantinos Dialynas, Yixin Sun, Qiugang Zong, Yixin Hao, Xuzhi Zhou   +7 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, Volume 20, Issue 8, Page 1933-1962, August 2026.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, Volume 20, Issue 8, Page 1913-1932, August 2026.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Dosimetric correlation between exit dose maps and anatomical changes in head and neck cancer treatment on Halcyon‐E: A gamma analysis approach

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Background Head and neck cancer (HNC) has a high incidence in Brazil. Although Image‐Guided Radiation Therapy (IGRT) improves treatment precision, anatomical changes during the treatment course may compromise dose distribution and require replanning.
Jayane Julia Pereira da Silva, Caio Weber Mendanha Ribeiro, Jaime Luiz Ludwig, Daniela Rocha Medrado, Bruno Nunes Melo da Silva, Ayane Cristine Alves Sarmento, Edilmar de Moura Santos   +6 more
wiley   +1 more source

Autoeficacia académica y ansiedad ante los exámenes en estudiantes de psicología de una universidad privada

Revista de Psicología, 2018
El objetivo de la investigación fue determinar si existen diferencias en cuanto a la ansiedad ante los exámenes entre estudiantes con alta y baja autoeficacia para situaciones académicas.
Sergio Dominguez Lara, Graciela Villegas García, Milagros Cabezas Cambillo, Stephanie Aravena Marcelino, Michael De la Cruz Valles   +4 more
doaj  

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

Detection, Attribution and Projection of Precipitation Structure Changes Over Northwest China

International Journal of Climatology, Volume 46, Issue 10, August 2026.
The precipitation structure shows a change trend of ‘the frequency of light precipitation decreased and the intensity of heavy precipitation increased’; attribution analysis shows that greenhouse gas forcing (GHG) is the main driving factor of precipitation structure change, and the model underestimates its impact, while aerosol forcing (AER) and ...
Shigen Wang, Wei Li, Lianyi Guo, Siyan Dong   +3 more
wiley   +1 more source

Propiedades psicométricas de una escala de autoeficacia para situaciones académicas en estudiantes universitarios peruanos

Revista de Psicología, 2018
El objetivo de este estudio consistió en analizar las propiedades psicométricas de la escala de autoeficacia percibida específica de situaciones académicas (eapesa) en una muestra de 249 estudiantes universitarios peruanos de edades comprendidas entre ...
Sergio Dominguez Lara, Carlos Yauri, Eduardo Mattos, Fernando Ramírez   +3 more
doaj