Results 51 to 60 of about 25,086 (222)

Clinical Applications of Phosphoproteomics: Illuminating Cancer Signaling and Enabling Rational Therapeutic Strategies

Cancer Science, EarlyView.
Mass spectrometry‐based phosphoproteomics for mechanistic dissection of cancer signaling pathways and uncovering therapeutic vulnerabilities. ABSTRACT Protein phosphorylation is a central post‐translational modification regulating cellular signaling, frequently dysregulated in cancer.
Hirokazu Shoji, Narikazu Boku, Jun Adachi   +2 more
wiley   +1 more source

Delipidisation of wool fibres and the subsequent beneficial properties of delipidised wool fibres

Coloration Technology, EarlyView.
Abstract Wool fibres are complex matrices of proteins and fatty acids/lipids found both internally and externally. 18‐methyleicosanoic acid (18‐MEA) is covalently bound to the surface of the fibre via a thio‐ester link, and is considered one of the most important lipids as it is responsible for the hydrophobic properties of wool fibres.
Jamie A. Hawkes, David M. Lewis
wiley   +1 more source

Beyond Negated Identity: Mediating the World History Classroom through Adorno's Negative Dialectics

Educational Theory, EarlyView.
Abstract This article centers on Adorno's negative dialectics to account for experiences of alienation and marginalization within the world history classroom. It begins with the problem of how marginalization occurs in high school world history classrooms with predominantly Black and Latinx students.
Tadashi Dozono
wiley   +1 more source

Metástase cervical nos tumores malignos da parótida

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Analisar fatores que influenciam a ocorrência de metástase linfática cervical e a sobrevida nos tumores malignos epiteliais da glândula parótida.
Roberto Araujo Lima, Marcos Roberto Tavares, Jacob Kligerman, Fernando Luiz Dias, Mauro Marques Barbosa, Claudio Roberto Cernea   +5 more
doaj   +1 more source

Golden weapons and golden fetters: From the gold standard to the new geopolitics

The Economic History Review, EarlyView.
Abstract This paper explores the historical relationship between monetary regimes, security concerns, and geopolitical tensions, particularly focusing on the role of gold. Throughout history, monetary systems have been deeply intertwined with international state systems and security provisions.
Harold James
wiley   +1 more source

Estudo da morbimortalidade cirúrgica, da sobrevida e dos fatores prognósticos dos pacientes portadores de sarcomas primários do retroperitônio

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar a morbimortalidade, sobrevida e os fatores prognósticos dos sarcomas primários do retroperitônio. MÉTODO: Análise retrospectiva de 59 pacientes com sarcoma de retroperitônio, operados na Seção de Cirurgia Abdomino-Pélvica do Instituto ...
Carlos Eduardo R. Santos, Orlando Marques Vieira, Mauro Monteiro Correa, Gustavo Santos Stoduto de Carvalho, Felipe Manzani, Jurandir de Almeida Dias   +5 more
doaj   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Ressecção de metástase hepática de sarcomas de partes moles

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar os resultados do tratamento cirúrgico de pacientes portadores de metástases hepáticas de sarcomas de partes moles, com ênfase na identificação de fatores prognósticos e estudo de sobrevida. MÉTODO: Foi realizada análise retrospectiva de
Rinaldo Gonçalves da Silva, Rubens Kesley Siqueira de Paiva, Carlos Eduardo Rodrigues Santos, Eduardo Linhares Riello de Melo, Jurandir de Almeida Dias, Guilherme Pinto Bravo Neto   +5 more
doaj   +1 more source

Law as a technology of exclusion: the legal construction of racialized and gendered work relations through the case study of international labour law in the first half of the twentieth century

Journal of Law and Society, EarlyView.
Abstract This article explores the role of labour law in processes of racialization and gendering of work. It argues that labour law not only protects certain forms of work (law as a protective mechanism), but also systematically excludes other forms of work, especially those performed by racialized and gendered individuals (law as a technology of ...
JULIETA LOBATO
wiley   +1 more source

Uso de Topotecan no tratamento do Tumor Epitelial de Ovário Refratário à Platina: Experiência do INCA

Revista Brasileira de Cancerologia, 2008
Introdução: O câncer de ovário é a principal causa de morte entre os tumores malignos ginecológicos nos Estados Unidos. Apesar dos avanços da terapia inicial, a maioria das pacientes apresentará recaída e necessitará de tratamento adicional.
Luiz Henrique de Lima Araújo, Fernando Meton de Alencar Câmara Vieira, Isabele Ávila Small , Paulo Alexandre Ribeiro Mora, Luciana Camillo Coura , Gustavo Henrique Gomes Advíncula   +5 more
doaj   +1 more source