Toward Personalized Theranostics: A Modular PET Platform for Antibody-Based Imaging and Therapy. [PDF]
Adv Sci (Weinh)This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Vivier D +16 more
europepmc +2 more sources
Cancer Expenditures and Mortality Trends in Brazil: An Ecological Population-Level Time-Series Analysis, 2008-2023. [PDF]
Cancer MedSchematic representation of the temporal relationship between increasing SUS‐recorded expenditures for breast and prostate cancer care in Brazil and comparatively limited changes in age‐standardized mortality, highlighting the potential influence of diagnostic delays, unequal access, healthcare infrastructure, and major oncology policy milestones.
Fonseca LS +4 more
europepmc +2 more sources
Syntaxin 12 Sustains Endosomal-Lysosomal Homeostasis and Survival in Glioblastoma Stem-Like Cells. [PDF]
TrafficSyntaxin12 maintains endolysosomal trafficking and lysosomal homeostasis in glioblastoma cells. Syntaxin12 depletion disrupts lysosomal organization, impairs endolysosomal progression and mTOR‐lysosome communication, and compromises adaptive pathways required for cell survival. ABSTRACT Glioblastoma cells display a striking vulnerability to disruptions
Maghe C +7 more
europepmc +2 more sources
bioinformatics-inca/KMT2Ar-prediction: v1.0
, 2022 Full Changelog: https://github.com/bioinformatics-inca/KMT2Ar-prediction/commits/v1.0 @tncristiane @
Cristiane Esteves
core +1 more source
Hail the Conquering Gods: Ritual Sacrifice of Children in Inca Society [PDF]
, 2012 The focus of this paper is to evaluate the Capacocha (also referred to as capac hucha) or child sacrifices in Inca society. This paper begins by evaluating the Capacocha ceremony as practiced by the Inca.
Faux, Jennifer L
core +1 more source
Health in the Inca heartland: A paleopathological analysis of burials from the Cuzco region of Peru
International Journal of Osteoarchaeology, 2021 AbstractWhile much is known about the rise and expansion of the Inca Empire (AD 1438–1532) throughout the Andean region of South America, the health effects of the empire in its capital region remain unclear. The present study addresses the Inca Empire's impact on health in the Cuzco region of Peru through an analysis of four conditions (dental enamel ...
openaire +2 more sources
Correction: Continuous versus intermittent infusion of β-lactams in patients with sepsis and septic shock: a systematic review and meta-analysis [PDF]
BMC Infectious DiseasesDavid A. Tejada +5 more
doaj +2 more sources
Open Archaeology, 2023 Abstract Pottery-making practices have been approached by the use and application of the concept of chaîne opératoire in different parts of the world. This concept has allowed researchers to re-evaluate the social dimensions of technological studies as well as to explore aspects related to technical and social identity of ancient and ...
Guillermo A. De La Fuente, Sergio Vera
openaire +2 more sources
Resabios de otros tiempos. Dominio incaico en los valles orientales del norte de Salta, Argentina
Bulletin de l'Institut Français d'Études Andines, 2014 This paper analyzes the modalities of the Inca occupation in the eastern valleys of the northern part of the present day Salta (Argentina). This study is based on an examination of previous research and the study of documents and colonial cartography and
Beatriz N. Ventura +1 more
doaj +1 more source
El Camino del Inca en el salar de Ascotán
Estudios Atacameños, 2023 Se da a conocer un subtramo del Camino del Inca de 24km de extensión en el sector oriental del salar de Ascotán, en la cordillera limítrofe entre Chile y Bolivia.
Rubén Stehberg +2 more
doaj +1 more source