Results 31 to 40 of about 973,008 (173)

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

Advanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin, Mehdi Liauzun, Jacobo Solorzano, Morgane Le Bras, Christine Jean, Benjamin Fourneaux, Margaux Dore, Lea Fevrier, Ismahane Belhabib, Alexia Brunel, Cindy Neuzillet, Marion Larroque, Carine Joffre, Stephane Rocchi, Nicolas Fraunhoffer, Aurelie Perraud, Muriel Mathonnet, Vera Pancaldi, Laetitia Linares, Juan Iovanna, Nelson Dusetti, Ola Larsson, Remy Nicolle, Stephane Pyronnet, Corinne Bousquet, Yvan Martineau   +25 more
wiley   +1 more source

A Geomorphometric Approach to Estimate the Deterioration of Earthen Archaeological Sites by Rainfall and Diffusion Processes: The Huaca Chornancap (Eighth–14th Century ad), Lambayeque, Peru

Archaeological Prospection, EarlyView.
ABSTRACT Rain‐induced erosion processes can severely damage Earthen archaeological sites. Huaca Chornancap (HCH; eighth–14th century ad) is a platform located in the Lambayeque region (Peru) exposed to seasonal rain due to El Niño Southern Oscillation (ENSO).
Luigi Magnini, Maria Ilaria Pannaccione Apa, Robert Gutiérrez Cachay, Marco Fernández Manayalle, Carlos Eduardo Wester La Torre, Guido Ventura   +5 more
wiley   +1 more source

Simultaneous Photoactivation of Copper and Ti‐Doped CeO2−x Enables Optimal Acceleration of the RWGS Reaction

Carbon Energy, EarlyView.
A combination of visible light and thermal energy accelerates the CO formation rate up to 57 times compared to dark conditions using a 3Cu/CeTiO2−x catalyst. Kinetic analysis, as well as steady state and transient spectroscopy, was applied under photocatalytic conditions to analyze and disentangle the reaction channels under dark and illuminated ...
Miha Okorn, Kristijan Lorber, Matjaž Mazaj, Nataša Novak Tušar, Petar Djinović   +4 more
wiley   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

Small, EarlyView.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk, Rima Nuwayhid, Stefaniya Gaydarova, Eva Bittrich, Natalia Makarova, Susanne Boye, Christo Tzachev, Jan C. Simon, Sandra Franz, Albena Lederer   +9 more
wiley   +1 more source

New discoveries on astronomical orientation of Inca site in Ollantaytambo, Peru

Geoinformatics FCE CTU, 2015
This paper deals with astronomical orientation of Incas objects in Ollantaytambo, which is located about 35 km southeast from Machu Picchu, about 40 km northwest from Cusco, and lies in the Urubamba valley.
Karolína Hanzalová, Jaroslav Klokočník, Jan Kostelecký   +2 more
doaj   +1 more source

Beyond Negated Identity: Mediating the World History Classroom through Adorno's Negative Dialectics

Educational Theory, EarlyView.
Abstract This article centers on Adorno's negative dialectics to account for experiences of alienation and marginalization within the world history classroom. It begins with the problem of how marginalization occurs in high school world history classrooms with predominantly Black and Latinx students.
Tadashi Dozono
wiley   +1 more source

Reducing stranded assets through early action in the Indian power sector

Environmental Research Letters, 2020
Cost-effective achievement of the Paris Agreement’s long-term goals requires the unanimous phase-out of coal power generation by mid-century. However, continued investments in coal power plants will make this transition difficult.
Aman Malik, Christoph Bertram, Jacques Despres, Johannes Emmerling, Shinichiro Fujimori, Amit Garg, Elmar Kriegler, Gunnar Luderer, Ritu Mathur, Mark Roelfsema, Swapnil Shekhar, Saritha Vishwanathan, Zoi Vrontisi   +12 more
doaj   +1 more source

Golden weapons and golden fetters: From the gold standard to the new geopolitics

The Economic History Review, EarlyView.
Abstract This paper explores the historical relationship between monetary regimes, security concerns, and geopolitical tensions, particularly focusing on the role of gold. Throughout history, monetary systems have been deeply intertwined with international state systems and security provisions.
Harold James
wiley   +1 more source

EL CAMINO DEL INCA ENTRE TOCOTA Y VILLA NUEVA (VALLE DE IGLESIA, SAN JUAN) / The Inka road between Tocota and Villa Nueva (Iglesia Valley, San Juan)

, 2011
La vialidad estatal incaica en los valles longitudinales de la provincia de San Juan, en el extremo SE del Tawantinsuyu, ha sido objeto de diversas consideraciones durante el u ltimo siglo.
Alejandro García
semanticscholar   +1 more source

Sharing Is Caring?—Pathogens and Pathogen‐Specific Antibodies in Arctic Endemic Seal Species and the Newly Sympatric Harbor Seals in Kongsfjorden, Svalbard

Marine Mammal Science, Volume 42, Issue 2, April 2026.
ABSTRACT Climate change associated transformations of Arctic marine ecosystems are having detrimental impacts on Arctic endemic marine mammals. However, warming conditions are providing new habitats for temperate marine mammals, some of which are expanding into Arctic regions, posing a threat of novel pathogen introduction and disease transmission.
Luca A. Schick, Kit M. Kovacs, Christian Lydersen, Simon Rohner, Ellen Prenger‐Berninghoff, Carsten Heydel, Christa Ewers, Alexander Postel, Nele Gremmel, Paul Becher, Christina Strube, Ursula Siebert   +11 more
wiley   +1 more source