TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo+11 more
wiley +1 more source
Information sharing and channel structure in e-commerce supply chain considering data-driven marketing. [PDF]
Han F, Wang M, Wu Z.
europepmc +1 more source
Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source
Impact of problem management-guided health education with positive incentive nursing after rectal cancer surgery. [PDF]
Mei CY, Zou F, Deng JM, Gong H.
europepmc +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
How to design better incentives for carbon capture and storage in the United States. [PDF]
Olmstead SM+6 more
europepmc +1 more source
Prevalence and inclusiveness of pay-for-performance incentives for HPV vaccination. [PDF]
Trogdon JG+3 more
europepmc +1 more source
Pathophysiological changes in incentive processing in episodic migraine: a preliminary event-related potential study. [PDF]
Liu C+7 more
europepmc +1 more source
Day-ahead economic dispatch of wind-integrated microgrids using coordinated energy storage and hybrid demand response strategies. [PDF]
Meng Q+4 more
europepmc +1 more source