Results 81 to 90 of about 158,250 (266)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Collective Innovation with Users:

open access: yesMaketingu Janaru, 2019
This research aims to explore the effective incentive for user innovators to achieve collective innovation between a company and users. This paper applied in-depth interviews for 17 participants of a user community that is organized by Apple and specific
Kei Aoki
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Blood donor incentives: A step forward or backward

open access: yesAsian Journal of Transfusion Science, 2010
Dramatic increase in blood usage and critical seasonal blood shortages are faced by various countries. Countries which previously reached 100% voluntary nonremunerated donation have been led to offer different kinds of incentives to recruit blood ...
Abolghasemi Hassan   +2 more
doaj  

PENGARUH PRIVACY CONCERNS, FINANCIAL LITERACY, INCENTIVE, DAN PERCEIVED EoU TERHADAP PERILAKU KEUANGAN DIGITAL MAHASISWA AKUNTANSI PERGURUAN TINGGI SWASTA DI YOGYAKARTA

open access: yesAkuntansi Dewantara
This study aims to identify the roles of privacy concerns, financial literacy, incentives, and Perceived Ease of Use (EoU) on e-wallet usage behavior.
Alfarisi Efendi   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

OPPORTUNITY AND INCENTIVE FOR BECOMING BILINGUAL IN COLOMBIA: IMPLICATIONS FOR PROGRAMA NACIONAL DE BILINGÜISMO OPORTUNIDADES E INCENTIVOS PARA VOLVERSE BILINGÜE EN COLOMBIA: IMPLICACIONES PARA EL PROGRAMA NACIONAL DE BILINGÜISMO

open access: yesIkala: Revista de Lenguaje y Cultura, 2012
The Programa Nacional de Bilingüismo (PNB) seeks to promote English proficiency in Colombian society in order to position Colombia within world communication processes, a global economy, and an increasingly multicultural world.
Jose David Herazo Rivera   +2 more
doaj  

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