Results 101 to 110 of about 532,047 (292)

Incentive Mechanism for Cloud Service Offloading in Edge–Cloud Computing Environment

open access: yesMathematics
Edge computing refers to provision storage and computation resources at the network edge, closer to end users than the remote cloud. In such edge–cloud computing environments, many cloud providers intend to offload cloud services to the edge nodes to ...
Chendie Yao, Junjie Xie, Zhong Liu
doaj   +1 more source

The Dynamic Pivot Mechanism [PDF]

open access: yes
We consider truthful implementation of the socially efficient allocation in an independent private-value environment in which agents receive private information over time. We propose a suitable generalization of the pivot mechanism, based on the marginal
Dirk Bergemann, Juuso Valimaki
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Announcement or Contribution? The Relative Efficiency of Manipulated Lindahl Mechanisms [PDF]

open access: yes
The private provision mechanism is individually incentive compatible but inefficient. The Lindahl mechanism is efficient but not incentive compatible. We analyze the outcome of the manipulated Lindahl mechanism.
Gareth Myles, Nigar Hashimzade
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

An Incentive Compatible Multi-Armed-Bandit Crowdsourcing Mechanism with Quality Assurance [PDF]

open access: yes, 2015
Consider a requester who wishes to crowdsource a series of identical binary labeling tasks to a pool of workers so as to achieve an assured accuracy for each task, in a cost optimal way.
Bhat, Satyanath   +4 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A geometric approach to mechanism design [PDF]

open access: yes
We develop a novel geometric approach to mechanism design using an important result in convex analysis: the duality between a closed convex set and its support function.
Alexey Kushnir, Jacob K. Goeree
core  

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