Results 61 to 70 of about 1,986 (212)
Design and analysis of enterprise management system framework based on blockchain
How to enhance the management of modern enterprises by blockchain technology has attracted more and more attention.ERP (enterprise resource planning) technology combined modern information technology with enterprise production process management,and ...
Wei ZHAO +3 more
doaj +3 more sources
Incentive Mechanisms for Peer-to-Peer Systems [PDF]
Most of the existing research in peer-to-peer systems focuses on protocol design and doesn’t consider the rationality of each peer. One phenomenon that should not be ignored is free riding. Some peers simply consume system resources but contribute nothing to the system.
Bin Yu 0006, Munindar P. Singh
openaire +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Federated learning optimization algorithm based on incentive mechanism
Federated learning optimization algorithm based on incentive mechanism was proposed to address the issues of multiple iterations, long training time and low efficiency in the training process of federated learning.Firstly, the reputation value related to
Youliang TIAN +4 more
doaj +2 more sources
Penalty mechanism in transactive energy: A mechanism design approach for day-ahead markets
Ensuring incentive compatibility mechanisms to enforce market obligations is crucial in deploying a transactive energy system. While previous studies have reported adopting penalty mechanisms for market compliance, these studies did not generally analyse
Alejandro Parrado-Duque +4 more
doaj +1 more source

