Results 61 to 70 of about 1,986 (212)

Design and analysis of enterprise management system framework based on blockchain

open access: yes网络与信息安全学报, 2019
How to enhance the management of modern enterprises by blockchain technology has attracted more and more attention.ERP (enterprise resource planning) technology combined modern information technology with enterprise production process management,and ...
Wei ZHAO   +3 more
doaj   +3 more sources

Incentive Mechanisms for Peer-to-Peer Systems [PDF]

open access: yes, 2004
Most of the existing research in peer-to-peer systems focuses on protocol design and doesn’t consider the rationality of each peer. One phenomenon that should not be ignored is free riding. Some peers simply consume system resources but contribute nothing to the system.
Bin Yu 0006, Munindar P. Singh
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Concurrent Treatment With Lorlatinib and Dinutuximab Beta Induced Acute Gastric Dilation in a Pediatric Patient With Neuroblastoma

open access: yes
Pediatric Blood &Cancer, EarlyView.
Suna Lin   +6 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Federated learning optimization algorithm based on incentive mechanism

open access: yesTongxin xuebao, 2023
Federated learning optimization algorithm based on incentive mechanism was proposed to address the issues of multiple iterations, long training time and low efficiency in the training process of federated learning.Firstly, the reputation value related to
Youliang TIAN   +4 more
doaj   +2 more sources

Penalty mechanism in transactive energy: A mechanism design approach for day-ahead markets

open access: yesEnergy Strategy Reviews
Ensuring incentive compatibility mechanisms to enforce market obligations is crucial in deploying a transactive energy system. While previous studies have reported adopting penalty mechanisms for market compliance, these studies did not generally analyse
Alejandro Parrado-Duque   +4 more
doaj   +1 more source

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