Results 241 to 250 of about 1,051,129 (331)

Assessing the Efficiency of Tax Incentives in the System for Managing Regional Finances

, 2016
Igonina Lyudmila Lazarevna, Mamonova Irina Vladimirovna, Сулейманов Магомед Магомедович   +2 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

RAIM: three-stage stackelberg game for hierarchical federated learning with reputation-aware incentive mechanism. [PDF]

Sci Rep
Zuo C, Xu P, Song Y, Lu J, Yuan C, Li Y.
europepmc   +1 more source

Impact of Culture on Incentive Systems : Findings from Swedish Organizations Operating in Japan and Korea

, 2011
Andreas Franzén, Linus Rogulla
openalex   +1 more source

The Hungarian Unemployment Insurance Benefit System and Incentives to Return to Work

, 2001
Joachim Wolff
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

The New Zealand System Level Measures Programme - a New Policy to Implement a Whole of System Performance Framework Using Health Alliances. [PDF]

Int J Integr Care
Sharma KM, Jones PB.
europepmc   +1 more source

Takeover likelihood and incentives system

, 2021
openaire   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Navigating the challenges in implementing financial incentives for behavior change at the intersection of human, animal, and ecosystem health: a case study. [PDF]

Sci One Health
Kerr JM, Delea MG, Chung M, Zhao J, Crawford J, Lapinski MK.   +5 more
europepmc   +1 more source