Results 121 to 130 of about 2,027,828 (376)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Reference with a Gimmick: A Pilot Program to Promote Library Services

open access: yesMarketing Libraries Journal, 2020
During the academic year 2018-2019, Yale University’s Bass Library piloted a reference program called Latte with a Librarian. The impetus for the pilot stemmed from a need for Yale librarians to engage more with students in-person and to market the ...
Blanchat, Kelly Marie, Sider, Laura
doaj  

Positive-Incentive Noise

open access: yesIEEE Transactions on Neural Networks and Learning Systems
Noise is conventionally viewed as a severe problem in diverse fields, e.g., engineering, learning systems. However, this paper aims to investigate whether the conventional proposition always holds. It begins with the definition of task entropy, which extends from the information entropy and measures the complexity of the task.
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

WHAT HAS HAPPENED TO REPLACEMENT RATES? ESRI Working Paper No. 76, May 1996 [PDF]

open access: yes, 1996
Financial incentives to take up and stay in work, and the impact of the tax and social welfare systems on these incentives, have become a major preoccupation of Irish policy-makers. Recent Budgets have highlighted measures to "reward work" through income
Callan, Tim   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Review of Producer Adoption in the U.S. Beef Industry with Application to Enteric Methane Emission Mitigation Strategies

open access: yesAnimals
Cattle are ruminant animals that produce enteric methane (CH4) emissions as a byproduct of their natural digestive process. U.S. beef producers have been receiving pressure to reduce production emissions.
Jaime R. Luke, Glynn T. Tonsor
doaj   +1 more source

Regulatory Investment Incentives [PDF]

open access: yes
This paper examines recent policy issues relating to foreign investment incentives in the regulatory domain. By 'regulatory incentives' in this context we mean those administrative conditions offered by governments to foreign firms other than special ...
Valpy FitzGerald
core  

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