Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
The Influence of Financial Incentives on Vaccination Hesitancy: A Narrative Review of Recent Research. [PDF]
Vaccines (Basel)Wong J, Gill C, Abdo A, Eisa A.
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Quantitative evaluation of China's commercial health insurance policies based on the policy modeling consistency index model. [PDF]
BMC Health Serv ResZhang L +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Incentivising participation in mental health app research: lessons learned from a mixed methods randomised controlled trial. [PDF]
BJPsych OpenBear HA, Money C, Watkins E, Fazel M.
europepmc +1 more source
Book Review: Organizational Behavior: Incentives and the Structure of Interest and Power in the Plant [PDF]
, 1971 Julius Rezler
openalex +1 more source
Incentives and motivation. [PDF]
Translational Issues in Psychological Science, 2016 Joshua Jessel +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
In depth exploration of drivers of community health workers' performance in maternal and child health services: a multistakeholder perspective from rural Indian setting. [PDF]
BMC Prim CareGouroumourty R +4 more
europepmc +1 more source