Results 81 to 90 of about 185,706 (247)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Reference with a Gimmick: A Pilot Program to Promote Library Services
Marketing Libraries Journal, 2020 During the academic year 2018-2019, Yale University’s Bass Library piloted a reference program called Latte with a Librarian. The impetus for the pilot stemmed from a need for Yale librarians to engage more with students in-person and to market the ...
Blanchat, Kelly Marie, Sider, Laura
doaj
IEEE Transactions on Neural Networks and Learning SystemsNoise is conventionally viewed as a severe problem in diverse fields, e.g., engineering, learning systems. However, this paper aims to investigate whether the conventional proposition always holds. It begins with the definition of task entropy, which extends from the information entropy and measures the complexity of the task.
openaire +3 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
AnimalsCattle are ruminant animals that produce enteric methane (CH4) emissions as a byproduct of their natural digestive process. U.S. beef producers have been receiving pressure to reduce production emissions.
Jaime R. Luke, Glynn T. Tonsor
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The tax system and the financial crisis
PSL Quarterly Review, 2011 This paper investigates the effects of the tax system on the economic factors that triggered the financial crisis. We examine three cases in which the tax regime interacted with these factors, reinforcing them.
Alessandra Sanelli +4 more
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