Results 121 to 130 of about 5,571,714 (295)

A rapid and ultra-sensitive dual readout platform for Klebsiella pneumoniae detection based on RPA-CRISPR/Cas12a

Frontiers in Cellular and Infection Microbiology
The bacterium Klebsiella pneumoniae (Kp) was the primary pathogen of hospital-acquired infection, but the current detection method could not rapidly and conveniently identify Kp.
Meiying Tan, Meiying Tan, Meiying Tan, Lina Liang, Lina Liang, Lina Liang, Chuan Liao, Chuan Liao, Chuan Liao, Zihan Zhou, Zihan Zhou, Zihan Zhou, Shaoping Long, Xueli Yi, Xueli Yi, Xueli Yi, Chunfang Wang, Chunfang Wang, Chunfang Wang, Caiheng Wei, Caiheng Wei, Caiheng Wei, Jinyuan Cai, Xuebin Li, Xuebin Li, Guijiang Wei, Guijiang Wei, Guijiang Wei, Guijiang Wei   +28 more
doaj   +1 more source

Ecoepidemics with a nonlinear disease incidence

, 2014
We present two new models for interacting populations subject to a transmissible disease. The novelty lies in the assumption that herd behavior influences the disease incidence, rather than the demographic description of the interactions, as in previous ...
Venturino, Ezio
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

A combination analysis based on bioinformatics tools reveals new signature genes related to maternal obesity and fetal programming

Frontiers in Medicine
BackgroundMaternal obesity significantly influences fetal development and health later in life; however, the molecular mechanisms behind it remain unclear.
Chunhong Liu, Chunhong Liu, Chunhong Liu, Yulan Lu, Chunchuan Huang, Chunchuan Huang, Chunchuan Huang, Yonglong Zeng, Yonglong Zeng, Yonglong Zeng, Yuye Zheng, Chunfang Wang, Chunfang Wang, Chunfang Wang, Huatuo Huang, Huatuo Huang, Huatuo Huang   +16 more
doaj   +1 more source

Diplomatic incident [PDF]

Nature, 2006
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Relationship between sarcopenia and fatty liver in middle-aged and elderly patients with type 2 diabetes mellitus

Journal of Orthopaedic Surgery and Research
Objective In this study, we investigated the relationship between sarcopenia and fatty liver in middle-aged and elderly patients diagnosed with type 2 diabetes mellitus (T2DM) to provide a theoretical foundation for the prevention and treatment of ...
Li Quan, Fang Zhang, Jing Xu, Fei Wang, Yong Fan   +4 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source