Results 121 to 130 of about 3,512,284 (307)

Incidence algebras. Overview [PDF]

, 2015
In his celebrated paper of 1964, "On the foundations of combinatorial theory I: Theory of Möbius Functions" Gian-Carlo Rota defined an incidence algebra as a tool for solving combinatorial problems.
Muge, Kanuni
core  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Targeting the PBX1–BCL2L1 axis as a therapeutic strategy in colorectal cancer

Cell Death Discovery
Pre-B-cell leukemia homeobox 1 (PBX1) is a transcription factor involved in diverse cellular processes, but its role in colorectal cancer (CRC) remains incompletely understood.
Hao Lin, Ting Su, Ying Liu, Ruilan Deng, Jie Li, Xuanhao Lin, Qiaoling Ke, Yijing Luo, Lele Meng, Bin Liang, Xuhong Song, Dongyang Huang, Lingzhu Xie   +12 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Incidence of Malignant Mesothelioma [PDF]

Mesothelioma is a cancer that forms in the tissue that lines many internal organs. The rate of new mesothelioma cases is going down because fewer people are exposed to asbestos.Mesothelioma is a cancer that forms in the mesothelium, the thin tissue that ...

core  

Joint association of physical activity and diet quality with dyslipidemia: a cross-sectional study in Western China

Lipids in Health and Disease
Objective This study aims to investigate the prevalence of dyslipidemia and assess the joint association of physical activity (PA) and diet quality on dyslipidemia risk in urban areas of Xinjiang.
Munire Mutalifu, Qian Zhao, Ying Wang, Xieyire Hamulati, Yu-Shan Wang, Lei Deng, Niyaziaili Adili, Fen Liu, Yi-Ning Yang, Xiao-Mei Li   +9 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

MIR155HG promotes metastasis and cisplatin resistance of cervical cancer cells by regulating the miR-409-3p and ZEB1 axis

Scientific Reports
Long non-coding RNA (lncRNA) exhibits a crucial role in multiple human malignancies. The expression of lncRNA MIR155HG, reportedly, is aberrantly up-regulated in several types of tumors.
Yanxia Chen, Jing Wang, Youqiang Heng, Yu Guo, Ka Ding, Cailing Ma   +5 more
doaj   +1 more source

Single-cell-derived ferroptosis signature predicts prognosis and therapy response in esophageal squamous cell carcinoma

Frontiers in Oncology
BackgroundEsophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis and limited therapeutic options. Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxidation, plays a crucial ...
Qin Xu, Yu Ma, Xuanqi Huang, Elyar abdukirim, Meng Yang, Chunli Song, Meng Liu   +6 more
doaj   +1 more source