Results 31 to 40 of about 2,822,691 (316)

Experimental study on the optimization of ANM33 release in foam cells

Open Life Sciences, 2023
Given the miR-33’s mechanistic relationships with multiple etiological factors in the pathogenesis of atherosclerosis (AS), we investigated the therapeutic potentials of dual-targeted microbubbles (HA-PANBs) in foam cell-specific release of anti-miR-33 ...
Yuan Chen, Liu Liyun, Tayier Baihetiya, Ma Ting, Guan Lina, Mu Yuming, Li Yanhong   +6 more
doaj   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

On the development and practice of translational medicine

生物医学转化, 2021
Translational medicine is an innovative research model that connects basic research and clinicalapplication. The development of translational medicine and the promotion of the transformation of results can provide advanced concepts and methods for the ...
Ayixiemuguli·Alimas, Wen Hao
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Aberrant activation of CYR61 enhancers in colorectal cancer development

Journal of Experimental & Clinical Cancer Research, 2019
Background High expression of secreted matricellular protein cysteine-rich 61 (CYR61) correlates with poor prognosis in colorectal cancer (CRC). Aberrant enhancer activation has been shown to correlate with expression of key genes involved in cancer ...
Lingzhu Xie, Xuhong Song, Hao Lin, Zikai Chen, Qidong Li, Tangfei Guo, Tian Xu, Ting Su, Man Xu, Xiaolan Chang, Long-Kun Wang, Bin Liang, Dongyang Huang   +12 more
doaj   +1 more source

Reducing incidence of postoperative acute kidney injury in trauma and orthopaedics patients: a quality improvement project [PDF]

, 2023
Sanat Kulkarni, T. Richardson, Alice E. Green, Radhika Acharya, Arusa Latif, Dakota Johnson, Huma Naqvi, Sreenadh Gella   +7 more
openalex   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury

Frontiers in Pharmacology
ObjectiveSepsis-associated acute kidney injury (SA-AKI) is a frequent and severe complication in septic patients. This study combines network pharmacology with in vitro and in vivo experiments to preliminarily investigate the protective effect of ...
Xuan Gou, Xuan Gou, Wei Zhang, Wei Zhang, Lele Wang, Lele Wang, Caixia Tan, Caixia Tan, Hong Wei, Hong Wei, Xinmin Wang, Xinmin Wang, Le Zhang, Le Zhang, Le Zhang   +14 more
doaj   +1 more source

Chemical incidents [PDF]

BJA Education, 2021
J P B, Sen, R, Sandhu, S, Bland
openaire   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source