Results 101 to 110 of about 2,088,818 (287)

Inclusión escolar: reflexiones desde las concepciones y opiniones de los docentes

open access: yes, 2010
Fil: Hernández Salazar, Vanesa. Universidad Nacional de La Plata. Facultad de Psicología.
Talou, Carmen Lidia   +5 more
openaire   +2 more sources

El Programa Presupuesto Participativo: participación ciudadana, democracia deliberativa e inclusión social : Análisis de las tensiones y potencialidades de la experiencia en Corrientes [PDF]

open access: yes, 2012
Fil: González Foutel, Laura M.. Universidad Nacional del Nordeste. Centro de Estudios Sociales.
Oraisón, María Mercedes   +1 more
openaire   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

La inclusión de medios digitales en la enseñanza de la Literatura: estallidos y discusiones de sentido en la producción de un booktráiler [PDF]

open access: yes, 2018
En este artículo presentamos algunos avances de un estudio estudio didáctico-disciplinar y etnográfico que tiene por objetivo comprender el alcance y las implicancias que los procesos de reforma e innovación impulsados a partir de la inclusión de medios digitales en la escuela secundaria de años recientes han tenido en la cotidianeidad de la cultura ...
Arias, Carolina   +1 more
openaire   +2 more sources

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

La política social en debate : Desigualdades, intervención estatal e inclusión social en la Argentina democrática [PDF]

open access: yes, 2013
Ya ha sedimentado en el sentido común académico que el modo en que se llevó adelante la transición democrática en Argentina produjo una brecha insalvable entre la preeminencia de los valores republicanos y liberales y la promesa de cumplir con el horizonte de justicia social.
openaire   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

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