Results 151 to 160 of about 3,577,384 (303)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Desafíos cotidianos para lograr la inclusión educativa: Producción de significados acerca de la discapacidad en el proceso de inclusión educativa preescolar [PDF]
Tesis (Magíster en Terapia Ocupacional, Mención Intervención Psicosocial)La presente investigación se enmarca en el desarrollo de la tesis para optar al grado de Magister en Terapia Ocupacional con mención Psicosocial, la cual tiene por objetivo analizar
Cereceda Román, Alejandra +1 more
core
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
La cultura de Weimar. La inclusión de lo excluido
Gerardo Meil Landwerlin, Peter Gay
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Parches, pandillas y sistema educativo en Bucaramanga: el reto de la inclusión
María Eugenia Bonilla Ovallos +1 more
openalex +2 more sources

