Results 181 to 190 of about 3,629,585 (302)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Effect of increasing prickly pear cactus (Nopalea cochenillifera) levels in diets of Holstein × Zebu dairy cows on nutrients intake and digestibility, ingestive behavior, and milk fatty acids profile. [PDF]
Rossa F +7 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
MASQ: A multiplex qPCR platform for quantitative alternative splicing analysis in clinical specimens. [PDF]
Jeong H, Cho N, Park JI, Yoo HJ, Kim KK.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Factors associated with social inclusion of parents of children with autism spectrum disorder: a multicenter cross-sectional study in China. [PDF]
Ji B +8 more
europepmc +1 more source

