Results 261 to 270 of about 3,577,384 (303)

The potential impact of changing the Norwegian trauma Registry inclusion criteria for patients not admitted with trauma team activation: Identifying patient groups to be excluded and considering potential risks. [PDF]

Eur J Trauma Emerg Surg
Nordberg S, Holm KT, Weber C, Røise O.
europepmc   +1 more source

Crisis económica y capital social: comunitarización y rehogarización de la inclusión

, 2014
Sandra Ezquerra Samper, Mariela Iglesias
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Demographics and Perceptions of Diversity, Equity, and Inclusion of the American College of Veterinary Ophthalmologists (ACVO) Members. [PDF]

Vet Ophthalmol
Kogan LR, Telle MR, Gibson TE.
europepmc   +1 more source

La inclusión de la historia de las mujeres en el nuevo paradigma educativo de la historia: análisis curricular y propuestas didácticas

, 2015
Carmen Suárez Suárez, Sonia García Galán   +1 more
openalex   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Epidermal inclusion cyst following type III female genital mutilation in a 10-year-Old girl: A rare pediatric presentation. [PDF]

Urol Case Rep
Abdi AM, Hassan AI, Mohamud AA, Kulle BM, Bashir AM.   +4 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Parental perceptions and attitudes towards the inclusion of children with neurodevelopmental, physical and sensory disabilities. [PDF]

Front Psychiatry
Kárpáti NV, Miklósi M.
europepmc   +1 more source

La otra cara de la política: exclusión e inclusión de las mujeres en el caso latinoamericano

, 1996
Lola G. Luna
openalex   +1 more source