Results 291 to 300 of about 3,577,384 (303)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Regulatory paradigm of Dscam1 stochastic alternative splicing through conserved long-range RNA structures. [PDF]

Nucleic Acids Res
Dong H, Xu B, Wu L, Wang Z, Li Z, Xie J, Lv J, Yang W, Bao N, Qu H, Fu J, Yan R, Wang Y, Li L, Shi F, Huang J, Yang X, Jin Y.   +17 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tactile-Sensation Imaging System for Assessing Material Inclusions in Breast Tumor Detection. [PDF]

Biosensors (Basel)
Nairuz T, Lee JH.
europepmc   +1 more source

Inclusión educativa de las personas con discapacidad en Colombia

, 2016
L.T. Hurtado
openalex   +1 more source

Effects of increasing narasin doses on feedlot performance, feeding behavior, carcass traits, and rumen-cecum morphometrics in Nellore cattle. [PDF]

PLoS One
Ferreira da Silva LA, Casali DM, Lélis ALJ, Leiva T, Rodrigues MC, Barroso JPR, Lasmar PVF, Araújo GLO, Virgínio Júnior GF, de Souza JM, Millen DD.   +10 more
europepmc   +1 more source

Physic-informed deep operator networks for modeling 2D time-domain electromagnetic wave propagation in various media. [PDF]

iScience
Oh S, Lee E, Hong SK.
europepmc   +1 more source

Supplementation of Hermetia Illucens Larvae to Improve Growth Performance, Meat Quality, and Intestinal Microbiology of Broiler in a Cost-Effective Manner. [PDF]

Vet Med Sci
Ahmed ST, Hassan MM, Parvin MM, Jannat T, Palash MRA.   +4 more
europepmc   +1 more source