Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
How employees of Korean franchise restaurants perceive older adult kiosk accessibility. [PDF]
Jang C, Kim S.
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Role of organizational network analyses to advance workforce inclusion and belonging: a scoping literature review. [PDF]
Decker-Tonnesen PL +7 more
europepmc +1 more source
Between rights and reality: patient perceptions of social inclusion in a forensic psychiatric clinic implementing safewards. [PDF]
Pelto-Piri V +4 more
europepmc +1 more source
Leisure time patterns of children with and without disabilities: a cross-sectional latent class analysis. [PDF]
Møller-Skau C +3 more
europepmc +1 more source
Teaching inclusion health principles: What medical students must learn to be prepared to work with marginalized populations. [PDF]
King B +4 more
europepmc +1 more source
Affect regulation in the context of sexual and gender minority stress: A scoping review protocol. [PDF]
Liu DY +5 more
europepmc +1 more source
Deciding to Be Left Alone After Being Left Out: Behavioral Responses to Social Exclusion in Schizophrenia. [PDF]
Weittenhiller LP, Kring AM.
europepmc +1 more source

