Results 141 to 150 of about 4,065,835 (293)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Impacts of hempseed and multicarbohydrase on growth performance, digestibility, intestinal morphology and microbial population of broilers. [PDF]

Poult Sci
Moaddab Gaskarei M, Shariatmadari F, Karimi Torshizi MA, Ahmadi H.   +3 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Co-production of a consensus-based inclusivity checklist to promote inclusion and diversity in clinical research: a multi-method study. [PDF]

BMJ Open
Cheng A, Aujla H, Grant R, Mowete C, Alhashimi A, Dearling J, Murray S, Page S, Mukuka E, Murphy G, Pufulete M, Equality, Diversity, and Inclusion Group of the National Cardiac Surgery Clinical Trials Programme.   +13 more
europepmc   +1 more source

Teachers' and parents' attitudes towards inclusion in inclusive schools in Saudi Arabia [PDF]

Implementation of educational inclusion policy has been shown to be influenced by a range of factors, such as leadership, training opportunities, collaborative teamwork and, the focus of this thesis, parents’ and teachers’ attitudes towards inclusion ...
Alanazi, Mona
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Safety of Multiple Sclerosis Treatments During Pregnancy: An Overview of the EU Regulatory Approach to Risk Management Planning. [PDF]

Pharmacoepidemiol Drug Saf
Strassmann V, Gault N, Stark AK, Vaillant T, Berbain T, Martirosyan L, Sarinic VM, Nordeng HME.   +7 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Relationship between age and ASQ-3 scores for each screening interval in Peruvian infants

Annals of Global Health, 2016
K.C. Chong, V.L. Zhou, D. Tarazona, H. Tuesta, J.E. Velásquez-Hurtado, F. Llanos   +5 more
doaj   +1 more source

<i>Chlamydia trachomatis</i> Hijacks Host Cell Programs to Establish Persistence. [PDF]

J Inflamm Res
Li X, Li Y, Teng W, Li J, Cai L, Chen H.
europepmc   +1 more source