Results 171 to 180 of about 1,278,840 (295)

Catalytically active inclusion bodies of cold-adapted lipase: production and its industrial potential. [PDF]

AMB Express
Bello MN, Sabri S, Yahaya NM, Shariff FM, Mohamad Ali MS.   +4 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Grass carp reovirus VP35 hijacks DHX15 into phase-separated inclusion bodies to evade host antiviral immunity. [PDF]

Cell Commun Signal
Zhang C, Lv Z, Zeng W, Zhang YA, Tu J.
europepmc   +1 more source

Recombinant human TIM-3 ectodomain expressed in bacteria and recovered from inclusion bodies as a stable and active molecule. [PDF]

Front Bioeng Biotechnol, 2023
Lima GC, Chura-Chambi RM, Morganti L, Silva VJ, Cabral-Piccin MP, Rocha V, Medina TS, Ramos RN, Luz D.   +8 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Expression, Solubilization, and Refolding Recovery of a Novel l‑Asparaginase-Arginase 1 Chimera from <i>E. coli</i> Inclusion Bodies. [PDF]

ACS Omega
Rivera MV, Gabriel Fontes M, Roldán WH, da Silva Junior RCV, Herrera Belén L, Beltrán JF, Lopes-Silva I, Pessoa A, Stephano MA, Farias JG, Costa-Silva TA, Monteiro G.   +11 more
europepmc   +1 more source

Imaging analysis reveals budding of filamentous human metapneumovirus virions and direct transfer of inclusion bodies through intercellular extensions. [PDF]

mBio, 2023
El Najjar F, Castillo SR, Moncman CL, Wu C-Y, Isla E, Velez Ortega AC, Frolenkov GI, Cifuentes-Munoz N, Dutch RE.   +8 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Coordinated interactions among Nipah virus N, P and M proteins drive formation of distinct inclusion bodies. [PDF]

J Gen Virol
Yasukochi M, Hosogi M, Kitai Y, Akahori Y, Ryo A, Takeda M, Katoh H.   +6 more
europepmc   +1 more source

Nipah Virus Impairs Autocrine IFN Signaling by Sequestering STAT1 and STAT2 into Inclusion Bodies. [PDF]

Viruses, 2023
Becker N, Maisner A.
europepmc   +1 more source