Results 221 to 230 of about 208,695 (255)

Update on Inclusion Body Myositis

Current Rheumatology Reports, 2018
While sporadic inclusion body myositis (sIBM) is the most common acquired muscle disease after age 50, the pathogenesis of this disease is still poorly understood. In this review, we discuss our current state of knowledge in sIBM and provide an update on our current understanding of its pathophysiology and management.Lines of evidence in support of an ...
Duaa, Jabari, V V, Vedanarayanan, Richard J, Barohn, Mazen M, Dimachkie   +3 more
openaire   +2 more sources

Amyloids in bacterial inclusion bodies

Trends in Biochemical Sciences, 2009
Protein misfolding and aggregation into amyloid structures are associated with dozens of human diseases. Recent studies have provided compelling evidence for the existence of highly ordered, amyloid-like conformations in the insoluble inclusion bodies produced during heterologous protein expression in bacteria.
Natalia S, de Groot, Raimon, Sabate, Salvador, Ventura   +2 more
openaire   +2 more sources

Hereditary inclusion body myopathies

Current Opinion in Neurology, 1998
Hereditary inclusion body myopathies comprise autosomal recessive and autosomal dominant muscle disorders that have a variable clinical phenotype but share similar morphological features. These include rimmed vacuoles within muscle fibres and collections of intrasarcoplasmic and intranuclear tubulofilamentous inclusions, 16-18 nm in external diameter ...
F M, Tomé, M, Fardeau
openaire   +2 more sources

Inclusion Body Myositis—A Review

Advances in Anatomic Pathology, 1998
Inclusion body myositis (IBM), a sporadic inflammatory myopathy, is the most frequently occurring progressive myopathy in adults older than 55 years. It more commonly affects men and usually is clinically and pathologically distinguishable from dermatomyositis or polymyositis.
openaire   +2 more sources

Leukocytapheresis in inclusion body myositis

Journal of Clinical Apheresis, 1987
AbstractA patient with inclusion body myositis was treated with a course of 22 leukocytaphereses combined with prednisone and azathioprine therapy. He improved clinically during an induction phase of frequent cytapheresis, which reduced the circulating levels of T lymphocytes and monocytes and decreased the ratio of the T4+ to T8+ lymphocyte subsets ...
openaire   +2 more sources

Intranuclear Inclusion Bodies

New England Journal of Medicine, 1973
A L, Florman, A A, Gershon
openaire   +2 more sources

Inclusion body myositis

Current Opinion in Rheumatology, 1989
R W, Kula, J A, Sawchak, J H, Sher
openaire   +2 more sources

Inclusion bodies are not uncommon in angioleiomyoma

Journal of Cutaneous Pathology, 2021
Satomi Igawa, Risa Matsuo, Mari Kishibe   +2 more
exaly  

Challenges Associated With the Formation of Recombinant Protein Inclusion Bodies in Escherichia coli and Strategies to Address Them for Industrial Applications

Frontiers in Bioengineering and Biotechnology, 2021
Weijun Wang, Ting Zhou, Yousef Hassan
exaly  

Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates

Journal of Biotechnology, 2006
Natalia Sanchez De Groot, Salvador Ventura   +1 more
exaly