Results 121 to 130 of about 15,592 (224)

Janus kinase and calcineurin‐inhibitor combination in anti‐MDA5 dermatomyositis: No significant survival benefit but reassuring safety profile

Journal of Internal Medicine, Volume 299, Issue 2, Page 228-240, February 2026.
Abstract Objectives Anti‐MDA5 dermatomyositis (anti‐MDA5 DM) is the most severe subtype of dermatomyositis, due to its pulmonary involvement. Current treatment involves corticosteroids and immunosuppressants, but variability in responses exists. This study aims to evaluate the efficacy and safety of Janus kinase (JAK)– and calcineurin–inhibitor ...
Valentine Pagis, Quentin Astouati, Lucas Pacoureau, Yann Nguyen, Pierre Bay, Antoine Roux, Laure Gallay, Vincent Cottin, Benjamin Terrier, Alain Meyer, Charles Cerf, Mathilde Neuville, Baptiste Hervier, Arthur Renaud, Benoit Suzon, Nicolas Schleinitz, Thomas Papo, Pascaline Priou, Arsène Mekinian, Audrey Ullmer, Erwan Oehler, Noémie Gensous, Alice Berezne, Luc De Saint Martin, Thierry Marhadour, Mickaël Martin, Amélie Servettaz, Maxime Samson, Laurent Gilardin, Pierre Charles, Juliette Woessner, Thierry Carmoi, Baptiste Dilly, Wladimir Mauhin, Nicolas Baillet, Sébastien Humbert, Benjamin Thoreau, Marine Lemaitre, Claire Le Pendu, Pierre Loiseau, Thomas Quemeneur, Elodie Blanchard, Nicol Voermans, David Launay, Hilario Nunes, Olivier Benveniste, Yurdagul Uzunhan, Yves Allenbach   +47 more
wiley   +1 more source

Dysphagia in Patients with Sporadic Inclusion Body Myositis: Management Challenges

International Journal of General Medicine, 2019
Nika Mohannak,1 Gemma Pattison,2 Kathryn Hird,1 Merrilee Needham1,3,4 1School of Medicine, The University of Notre Dame, Fremantle, Western Australia, Australia; 2Department of Speech Pathology, Royal Perth Hospital, Perth, Western Australia, Australia ...
Mohannak N, Pattison G, Hird K, Needham M   +3 more
doaj  

Strenuous Exercise Alters Brain Creatine and Glutamate/Glutamine (Glx) in Humans: Evidence From Dynamic 1H‐MRS and 1H‐MRSI

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Strenuous exercise induces transient, region‐specific neurochemical changes in the human brain. Dynamic proton magnetic resonance spectroscopy (1H‐MRS) and spectroscopic imaging (1H‐MRSI) revealed reductions in total creatine (tCr), and elevations in glutamate/glutamine (Glx), and lactate (Lac) in frontal and parietal brain regions.
Jedd Pratt, Antonia Kaiser, Libby Henthorn, Oliver Mundell, Elise From, Aneurin J. Kennerley, Craig Sale   +6 more
wiley   +1 more source

Neurological complications of immune checkpoint inhibitors: what happens when you \u27take the brakes off\u27 the immune system. [PDF]

, 2018
Patients with advanced malignancies treated with immune checkpoint inhibitors are at increased risk for developing immune-related neurological complications.
Dalakas, Marinos
core   +1 more source

Inclusion Body Myositis [PDF]

, 2020
Schmidt, Karsten, Schmidt, Jens
  +6 more sources

Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle. [PDF]

, 2008
Distinct interrelationships between inflammation and beta-amyloid-associated degeneration, the two major hallmarks of the skeletal muscle pathology in sporadic inclusion body myositis (sIBM), have remained elusive.
Barthel, Konstanze, Bähr, Mathias, Dalakas, Marinos C, Salajegheh, Mohammad, Schmidt, Jens, Wrede, Arne   +5 more
core   +1 more source

Capabilities of magnetic resonance imaging in the diagnosis of idiopathic inflammatory myopathies

Научно-практическая ревматология
Idiopathic inflammatory myopathies (IIM) are a group of chronic autoimmune conditions characterized by proximal muscle weakness and potentially accompanied by a range of extramuscular clinical manifestations.
A. A. Kolomeychuk
doaj   +1 more source

Determining the Characteristic Vocabulary for a Specialized Dictionary using Word2vec and a Directed Crawler [PDF]

, 2016
Specialized dictionaries are used to understand concepts in specific domains, especially where those concepts are not part of the general vocabulary, or having meanings that differ from ordinary languages.
Grefenstette, Gregory, Muchemi, Lawrence
core   +3 more sources

Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers [PDF]

, 2019
Desmin-associated myofibrillar myopathy (MFM) has pathologic similarities to neurodegeneration-associated protein aggregate diseases. Desmin is an abundant muscle-specific intermediate filament, and disease mutations lead to its aggregation in cells ...
Arhzaouy, Khalid, Batchelor, Mark, Bieschke, Jan, Kedia, Niraja, Pittman, Sara K., Sun, Yuanzi, Weihl, Conrad C.   +6 more
core   +1 more source

Inclusion body myositis — a case based clinicopathological update

Open Medicine, 2014
Bodoki Levente, Vincze Melinda, Griger Zoltán, Csonka Tamás, Murnyák Balázs, Kurucz Andrea, Dankó Katalin, Hortobágyi Tibor   +7 more
doaj   +1 more source