Emerging therapeutic options for sporadic inclusion body myositis
Lindsay N Alfano, Linda P Lowes Nationwide Children’s Hospital, Center for Gene Therapy, Columbus, OH, USA Abstract: Sporadic inclusion body myositis is the most common inflammatory muscle disorder preferentially affecting males over the age of ...
Alfano LN, Lowes LP
doaj
Multicenter questionnaire survey for sporadic inclusion body myositis in Japan
Background Sporadic inclusion body myositis (sIBM) is the most prevalent acquired muscle disease in the elderly. sIBM is an intractable and progressive disease of unknown cause and without effective treatment.
Naoki Suzuki +19 more
doaj +1 more source
Autoantibodies against a 43 KDa muscle protein in inclusion body myositis. [PDF]
BACKGROUND: Inclusion body myositis (IBM) is a poorly understood and refractory autoimmune muscle disease. Though widely believed to have no significant humoral autoimmunity, we sought to identify novel autoantibodies with high specificity for this ...
Mohammad Salajegheh +2 more
doaj +1 more source
The EuroMyositis registry: an international collaborative tool to facilitate myositis research [PDF]
Aims: The EuroMyositis Registry facilitates collaboration across the idiopathic inflammatory myopathy (IIM) research community. This inaugural report examines pooled Registry data.
Andersson, Helena +27 more
core +7 more sources
The inclusion body myositis is an inflammatory myopathy that leads to chronic muscle inflammation associated with muscle weakness. It is characterized by a restrictive ventilatory syndrome requiring ventilatory support under non-invasive ventilation. The
Ana Marinho +3 more
doaj +3 more sources
Treatment of inclusion body myositis: is low-dose intravenous immunoglobulin the solution? [PDF]
Inclusion body myositis (IBM), the most common inflammatory myopathy in the elderly, is often resistant to various forms of therapy. Placebo-controlled treatment trials with high dose intravenous immunoglobulins (IVIG) have shown disease amelioration in ...
Arndt, Börge +5 more
core
Manual muscle testing and hand-held dynamometry in people with inflammatory myopathy : an intra- and interrater reliability and validity study [PDF]
Manual muscle testing (MMT) and hand-held dynamometry (HHD) are commonly used in people with inflammatory myopathy (IM), but their clinimetric properties have not yet been sufficiently studied.
Baschung Pfister, Pierrette +5 more
core +1 more source
Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman +2 more
wiley +1 more source
Anesthetic management of a hydrocephalus patient with inclusion body myositis
Inclusion body myositis (IBM) is an inflammatory muscle disease characterized by slowly progressive muscle weakness and wasting, especially affecting proximal leg and distal arm.
Daiki Takekawa +5 more
doaj +1 more source
Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England [PDF]
Concerns have been raised over breed-related health issues in purebred dogs, but reliable prevalence estimates for disorders within specific breeds are sparse.
Brodbelt, D C +5 more
core +3 more sources

