Results 121 to 130 of about 1,231,942 (313)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
i-comParticipatory processes are key for designing technology solutions but challenging since target groups rarely have technological expertise. They are, however, experts in their lives.
Mildenberger Tabea +2 more
doaj +1 more source
INVESTIGATING INCLUSIVE DESIGN OF SHARED AUTOMATED VEHICLES WITH FULL-SCALE MODELING. [PDF]
Proc Hum Factors Ergon Soc Annu Meet, 2021 Tabattanon K, Schuler PT, D'Souza C.
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Understanding the Influences of COPD Patient's Capability on the Uptake of Pulmonary Rehabilitation in the UK Through an Inclusive Design Approach. [PDF]
Int J Chron Obstruct Pulmon Dis, 2021 Liu Y +5 more
europepmc +1 more source
Understanding quality in inclusive research: a process of dialogue
, 2013 The case for research by and with (rather than on) people with learning disabilities has been successfully made. Calls for emancipatory research have drawn attention to the ways that research owned by disabled people can better tackle social oppression ...
Nind, Melanie
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Inclusive design: making packaging easier to open for all [PDF]
Social equality demands a shift in attitude, away from treating older people and people with disabilities as special cases requiring special design solutions, and towards enabling them to have equal access to any product or service through a more ...
Janson, Rob +3 more
core
The Summit on Creativity and Aging in America [PDF]
, 2016 This report looks at how the federal government can leverage the arts to foster healthy aging and inclusive design for this growing population. This white paper features recommendations from the May 2015 Summit on Creativity and Aging in America, a ...
Ace Everett +7 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source