Results 141 to 150 of about 1,226,951 (342)

Applying the Analytic Hierarchy Process (AHP) to Accessible Housing: A Multi-Disability Perspective

Disabilities
Accessible housing plays a vital role in promoting independent living and quality of life for people with disabilities. However, the existing design standards often fail to address the specific needs of diverse disability groups.
Claudia Valderrama-Ulloa, Ximena Ferrada, Felipe Herrera   +2 more
doaj   +1 more source

E Is for Everyone: The Case for Inclusive Game Design [PDF]

, 2008
Part of the Volume on the Ecology of Games: Connecting Youth, Games, and Learning In this chapter I examine the accessibility of today's games, or rather the lack of.
Amit Pitaru
core  

Integration of Conversion Factors for the Development of an Inclusive eHealth Tool With Caregivers of Functionally Dependent Older Persons: Social Justice Design (Preprint)

, 2020
Karine Latulippe, Christine Hamel, Dominique Giroux   +2 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Details on the Design and Evaluation Process of an Educational Game Considering Issues for Visually Impaired People Inclusion

Educational Technology & Society, 2019
In the last decade many studies have stated that learning based on digital games emerges as an effective way to combine teaching and learning processes with the attractiveness of digital technologies, because they are dynamic and playful.
Luiz Valério Neto, Paulo H. F. Fontoura Junior, Rogério A. Bordini, Joice L. Otsuka, Delano M. Beder   +4 more
doaj  

The role of flow experience in codesigning open-design assistive devices [PDF]

, 2011
This paper describes the theoretical framework of an inclusive participatory design approach which leads to qualitative occupational experiences within the field of community-based rehabilitation.
De Couvreur, Lieven, Detand, Jan, Goossens, Richard   +2 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Beyond Accessibility Compliance: Exploring the Role of Information on Apparel Shopping Websites for the Blind and Visually Impaired

Societies
In response to increasing numbers of people switching from offline to online shopping after the COVID-19 pandemic, this study sought to obtain an in-depth understanding of apparel website design and digital accessibility for all people, including people ...
Emma Nicoson, Jung Ha-Brookshire
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Multisensory inclusive design with sensory substitution. [PDF]

Cogn Res Princ Implic, 2020
Lloyd-Esenkaya T, Lloyd-Esenkaya V, O'Neill E, Proulx MJ.   +3 more
europepmc   +1 more source