Results 141 to 150 of about 1,231,942 (313)
Can the sports design process help the inclusive design community? [PDF]
, 2015 As the global population ages, inclusive design is becoming more important to companies due to customer demands and increased competition. It is also acknowledged that the use of a formalised design process is of commercial benefit to a company. There is
Riches, Philip +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The role of flow experience in codesigning open-design assistive devices [PDF]
, 2011 This paper describes the theoretical framework of an inclusive participatory design approach which leads to qualitative occupational experiences within the field of community-based rehabilitation.
De Couvreur, Lieven +2 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Northumbria University Institutional Case Study: Meaningful Student Engagement Programme, Higher Education Academy [PDF]
“Student engagement is concerned with the interaction between the time, effort and other relevant resources invested by both students and their institutions intended to optimise the student experience and enhance the learning outcomes and development of ...
Bradshaw, Kate +5 more
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Cat Housing: A Case for Inclusive Cohabitation [PDF]
, 2016 This major research project (MRP), focused on inclusive industrial design, is a continuation of the "Fumao Jihua" (福猫计划) or the “Cat's Paradise” Project for rescuing stray cats that I was engaged in between 2011 and 2013 in Xi'an, China.
Xie, Songfeng (Koni)
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The impact of curriculum content in fostering inclusive engineering: data from a national evaluation of the use of EWB projects in first year engineering [PDF]
, 2011 The year of Humanitarian Engineering draws our attention to the need to develop engineers who are not just technically competent but who can effectively address the needs of communities, maintain their ethical responsibilities, and take sustainability ...
Brodie, Lyn +4 more
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source