Results 181 to 190 of about 1,250,319 (355)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

A Braille Trail for all: Inclusive design in the Karoo Desert National Botanical Garden. [PDF]

Afr J Disabil
Greyling SF, Verhoef SM, Tempelhoff WGDV.   +2 more
europepmc   +1 more source

Navigating Africa's Resource Economy: Debt Resolution and Policy Design for Sustainable and Inclusive Economic Recovery

International Conference on Africa's Sustainable Development (ICASuD)
openalex   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Toward Normalizing Inclusive Design by Uncovering Patient Experiences of a Web Portal in a Dental Hospital: Mixed Methods Study. [PDF]

J Med Internet Res
Bamgboje-Ayodele A, Raubenheimer J, Paonne A, Yi J, Jayawardena T, Ajwani S, Szuba E, Chowdhury T, Dao P, Ahmed M, Von Huben A, Howell M, Nixon N, Dunn A, Jones A, Baysari M.   +15 more
europepmc   +1 more source

DBA design challenge: Engaging design professionals with inclusive design [PDF]

, 2005
Cassim, J, Dong, H
core  

Think tanks: A case study for the co-design of inclusive learning spaces

Austin, Richard
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A value hierarchy for inclusive design of heart valve implants in regenerative medicine. [PDF]

Regen Med
De Kanter AJ, Daal MV, Gunn CJ, Bredenoord AL, Graeff N, Jongsma KR.   +5 more
europepmc   +1 more source