Results 241 to 250 of about 1,226,951 (342)

Can You See Us Play? Observing Inclusive Outdoor Play Behaviour Among Children With and Without Disabilities: A Mixed Methods Study. [PDF]

Child Care Health Dev
Beekhuizen RQ, Bloemen MAT, Bolster EAM, Visser K, van der Lugt R, Bassa M, Henry NL, Kotte EMW, van Hartingsveldt M, Gorter JW.   +9 more
europepmc   +1 more source

Using UX Design in inclusive teacher education in higher education to bridge the research-to-practice gap

Ines Oldenburg, Clemens Hillenbrand
openalex   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Inclusive and sustainable active mobility: recommendations for older adults in Montenegro. [PDF]

Front Physiol
Popovic S, Babayigit Irez G, Masanovic B.   +2 more
europepmc   +1 more source

Think tanks: A case study for the co-design of inclusive learning spaces

Austin, Richard
openalex   +1 more source

Diversity Of Responses And Potential Conflicts In Inclusive Urban Sound Design – Preliminary Results From Interviews In Brighton (UK) [PDF]

Mattia Cobianchi, Lisa Lavia, John L. Drever   +2 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Inclusive climates and employee voice behavior: the roles of voice efficacy and voice channel design. [PDF]

Front Psychol
Shen W, Shen L.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Current trends in art and design for paediatric wellness in built environments (2020-2025): a thematic review. [PDF]

Front Pediatr
Zairul M, Hafizah N.
europepmc   +1 more source