Results 241 to 250 of about 1,231,942 (313)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Adjustments and Vocational Aspirations of Deaf Blindness Students. [PDF]

Ann Neurosci
Kumar N, Singh G, Agrawal PK, Kumar A, Kumar A, Tiwari PK.   +5 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

ICU Nurses' Perceptions of Family-Inclusive Outdoor Excursions: Enhancing Family Engagement and Humanisation in Intensive Care. [PDF]

Nurs Crit Care
Sasano N, Odajima Y.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Equitable inclusion of people with disabilities in clinical trials: a scoping review. [PDF]

BMJ Open
Jo G, Castro F, Cerilli C, Varadaraj V, Rosman L, Kamenov K, Barrett D, Swenor B.   +7 more
europepmc   +1 more source

Effective mediation strategies for addressing social communication disorder in inclusive primary classrooms: Implications for teacher training. [PDF]

Afr J Disabil
Molekoa MA, Malahlela MK.
europepmc   +1 more source

Development and Formative Usability Evaluation of a Theory-Driven Progressive Web Application for Young Adult Wellness Engagement (MiCARE): Protocol for a Mixed Methods Study.

JMIR Res Protoc
Thanthrige A, Wickramasinghe N.
europepmc   +1 more source

Empowering Adolescents for Sustainable and Inclusive Careers: A Quasi-Experimental Evaluation of a Life Design-Based Intervention. [PDF]

J Adolesc
Santilli S, Zucchini D, Valbusa I, Ginevra MC, Tracey T, Nota L.   +5 more
europepmc   +1 more source