Results 81 to 90 of about 1,231,942 (313)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Designing diversity: ethical virtual agents for effective dermatological training

open access: yesFrontiers in Virtual Reality
This paper discusses the importance of diversity and inclusivity in designing virtual agent simulations for dermatology. As virtual reality (VR) technology become increasingly utilized in dermatological diagnosis, treatment, and training, there is a need
Melisa Kujević   +4 more
doaj   +1 more source

Inclusive Design in Assisted Instruction [PDF]

open access: yes
Much instruction starts with abstract representations for which learners have insufficient foundation [1]. The British Standard, BS 7000-6:2005 Guide to Managing Inclusive Design, provides a comprehensive framework that can help all private enterprises ...
Gabriel ZAMFIR
core  

Inclusive design: developing students' knowledge and attitude through empathic modelling [PDF]

open access: yes, 2013
Cataloged from PDF version of article.To enhance the function and quality of built environments, designers should consider all possible users in their design projects.
Altay, B., Demirkan, H.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Universal Design in Interior Architecture Education: The Case of Store Design

open access: yesIconarp International Journal of Architecture and Planning, 2019
Universal design is a user-focused designing approach that involves cultural, physical, mental and dimensional aspects and takes into account the needs of different personal characteristics.
Sariye Selhan Yalçın Usal   +1 more
doaj  

Design factors for a successful Shared Space Street (SSS) design

open access: yesInternational Journal of Strategic Property Management, 2018
The concept of Shared Space Street (SSS) has the potential to bring many benefits to a city. Those include promotion of social interaction, the connectivity within the city for both vehicles and pedestrians, active engagement of the people with the space,
Ranmalsingha R. J. C. Jayakody   +3 more
doaj   +1 more source

Disability-aware adaptive and personalised learning for students with multiple disabilities [PDF]

open access: yes, 2017
Purpose The purpose of this paper is to address how virtual learning environments (VLEs) can be designed to include the needs of learners with multiple disabilities.
Brayshaw, Mike, Nganji, Julius T.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Designing Artificial Intelligence: Exploring Inclusion, Diversity, Equity, Accessibility, and Safety in Human-Centric Emerging Technologies

open access: yesAI
Background: The implementation of artificial intelligence (AI) has become a pivotal interdisciplinary challenge, creating new opportunities for sharing information, driving innovation, and transforming societal interactions with technology.
Matteo Zallio   +2 more
doaj   +1 more source

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