A mechanically robust, self‐healable, moisturizing, cryotolerant and adhesive GelMA hydrogel is developed by incorporating polyvinyl alcohol, acrylic acid, sodium tetraborate, and glycerol into GelMA matrix via a photoinitiated polymerization process. The hydrogel‐derived omni‐healable ionotronic pressure sensor can sensitively and consistently monitor
Zhikang Li +16 more
wiley +1 more source
The impact of intratumor heterogeneity on outcome and resistance to therapy in primary breast cancer: a systematic review. [PDF]
Dianati A, Dekker A, Wesselius A, Wee L.
europepmc +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
A novel three-parameter Gompertz-Lomax Distribution with a physics-informed survival network: statistical theory, hazard shape characterization, and real-world applications. [PDF]
P FA, V S.
europepmc +1 more source
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao +15 more
wiley +1 more source
Simulation-based approach with an adaptive Type-II hybrid progressive censoring scheme to study the coefficient of variation of the weighted exponential distribution. [PDF]
Aljohani HM +5 more
europepmc +1 more source
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li +13 more
wiley +1 more source
Gain-adaptive STAR-RIS assisted vehicular NOMA with transmit antenna selection. [PDF]
Ibraheem SM +3 more
europepmc +1 more source
Mutant KRAS‐m6A Epitranscriptome Axis Promotes Colorectal Cancer and is a Therapeutic Target
Mutant KRAS‐m6A axis promotes colorectal cancer (CRC) progression. Mutant KRAS stabilizes METTL3, leading to increased m6A‐modified BCL9L mRNA and translation of BCL9L protein. BCL9L in turn mediates TGF‐β secretion to induce differentiation of Treg and an immunosuppressive microenvironment.
Danyu Chen +12 more
wiley +1 more source
The Wells-Riley Model Revisited II: Parameter Uncertainty and Population Heterogeneity. [PDF]
Marshall M +7 more
europepmc +1 more source

