Results 61 to 70 of about 349,789 (305)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Filter design, fault estimation and reliable control for networked time-varying systems: a survey

Systems Science & Control Engineering, 2017
This paper is concerned with the overview of the recent progress in filter design, fault estimation and reliable control for networked time-varying systems (NTVSs).
Jiahui Li, Hongli Dong, Fei Han, Nan Hou, Xuerong Li   +4 more
doaj   +1 more source

Implementasi Limited Tolerance Relation Untuk Sistem Informasi yang Tidak Lengkap Pada Data Mahasiswa

Fountain of Informatics Journal, 2018
Rough set theory is one of the mathematical models for dealing with a vague, imprecise, and fuzzy knowledge that has been successfully used to handle incomplete information systems.
Edi Sutoyo
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Recent advances on filtering and control for nonlinear stochastic complex systems with incomplete information: A survey

, 2011
This Article is provided by the Brunel Open Access Publishing Fund - Copyright @ 2012 Hindawi PublishingSome recent advances on the filtering and control problems for nonlinear stochastic complex systems with incomplete information are surveyed.
Liu, Y, Zidong Wang, Wang, Z, Liang, J, Yurong Liu, Bo Shen, Shen, B, Jinling Liang   +7 more
core   +1 more source

A Bayesian Stackelberg Game Approach to Remote State Estimation Under SINR-Based DoS Attacks with Incomplete Information

Sensors
With limited energy constraints, the issue of transmission and interference strategies have received considerable critical attention in cyber–physical security.
Di Deng, Peng Yi, Mingze Qi
doaj   +1 more source

Approximate Accuracy Approaches to Attribute Reduction for Information Systems

Abstract and Applied Analysis, 2014
The key problem for attribute reduction to information systems is how to evaluate the importance of an attribute. The algorithms are challenged by the variety of data forms in information system.
Deshan Liu, Dapeng Wang, Deqin Yan, Yu Sang   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

XML with incomplete information [PDF]

, 2009
We study models of incomplete information for XML, their computational properties, and query answering. While our approach is motivated by the study of relational incompleteness, incomplete information in XML documents may appear not only as null values ...
Leonid Libkin, Libkin, Leonid, Barcelo, Pablo, Poggi, Antonella, Sirangelo, Cristina, Antonella Poggi, Pablo Barcelo, Cristina Sirangelo   +7 more
core   +1 more source