Effects of the γ-secretase inhibitor semagacestat on hippocampal neuronal network oscillation
Frontiers in Pharmacology, 2013 Neurological and psychiatric disorders are frequently associated with disruption of various cognitive functions, but development of effective drug treatments for these conditions has proven challenging.
Mihaly eHajos +8 more
doaj +1 more source
Molecular Generative Model via Retrosynthetically Prepared Chemical Building Block Assembly
Advanced Science, 2023 Deep generative models are attracting attention as a smart molecular design strategy. However, previous models often render molecules with low synthesizability, hindering their real‐world applications.
Seonghwan Seo +2 more
doaj +1 more source
Incorporation of biguanide compounds into poly(GL)-b-poly(GL-co-TMC-co-CL)-b-poly(GL) monofilament surgical sutures [PDF]
, 2017 A new biodegradable coating was developed for bioabsorbable monofilament sutures. Specifically, a random copolymer having 35 wt-% and 65 wt-% of lactide and trimethylene carbonate units showed appropriate flexibility, stickiness and degradation rate, as ...
Cabral, Tània +6 more
core +2 more sources
Autotransformer starting mode study for large compressor motor
You-qi chuyun, 2023 Compressor is the core process equipment of the refining and chemical enterprises, long-distance natural gas pipeline compressor stations, gas injection stations of gas storage, etc.
CUI Wanji
doaj +1 more source
Harmonic Mitigation Using Passive Harmonic Filters: Case Study in a Steel Mill Power System
Energies, 2021 In this study, we mitigated the harmonic voltage in a power system that contained the roughing mill (RM) and finishing mill (FM) motor drives. AC/DC converter type RM drive is a non-linear, large-capacity varying load that adversely affects power quality,
Byungju Park +3 more
doaj +1 more source
Applied Sciences, 2021 Bacterial vaginosis (BV) is the most common vaginal infection globally, with a high recurrent rate after antibiotic treatment. Probiotics consumption is known to improve BV with different efficacy among species or strains.
Ta-Chin Lin +9 more
doaj +1 more source
Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles [PDF]
, 2013 We previously reported that the incorporation of tissue factor (TF) into cell-derived microvesicles (MVs) is regulated by the phosphorylation of the cytoplasmic domain of TF.
Collier, Mary E. W. +2 more
core +1 more source
Using Ground Targets to Validate S-NPP VIIRS Day-Night Band Calibration
Remote Sensing, 2016 In this study, the observations from S-NPP VIIRS Day-Night band (DNB) and Moderate resolution bands (M bands) of Libya 4 and Dome C over the first four years of the mission are used to assess the DNB low gain calibration stability.
Xuexia Chen +5 more
doaj +1 more source
Inhibition of geranylgeranyl diphosphate synthesis in in vitro systems [PDF]
, 1985 The incorporation of [14C]mevalonate and [14C]isopentenyl diphosphate into geranylgeranyl diphosphate was investigated in in vitro systems from Cucurbita pepo (pumpkin) endosperm and from Avena sativa etioplasts.
Mitzka-Schnabel, Ursula +4 more
core +1 more source
Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitution. [PDF]
, 2016 RNA polymerase II (pol II) utilizes a complex interaction network to select and incorporate correct nucleoside triphosphate (NTP) substrates with high efficiency and fidelity.
Chong, Jenny +10 more
core +3 more sources