Results 51 to 60 of about 948,923 (276)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Selective Growth of Homo-Epitaxial Ag-Nano-Layer on Tribo-Assisted-Reorientation

Tribology Online, 2008
The growth process and orientational degree of incremental-Ag films with a thickness of 5, 50 and 500 nm, respectively, on reoriented Ag (111) surface were studied by in-situ reflection high-energy electron diffraction (RHEED).
Minoru Goto, Hiroaki Kobayashi, Koichi Akimoto   +2 more
doaj   +1 more source

Characteristics of micro incremental in-plane bending of sheet metal using tiltable punch [PDF]

, 2013
Incremental forming methods have gained interest in recent years as a forming technique for micro and fine components. This paper presents a newly developed incremental in-plane bending with tiltable punch for micro-metal sheets whose thickness is less ...
Azrie, Ahmad, Kuboki, Takashi
core  

Linear Encodings of Bounded LTL Model Checking

, 2006
We consider the problem of bounded model checking (BMC) for linear temporal logic (LTL). We present several efficient encodings that have size linear in the bound.
Armin Biere, Keijo Heljanko, Kousha Etessami, Timo Latvala, Tommi Junttila, Viktor Schuppan   +5 more
core   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

A Tutorial on Incremental Stability Analysis using Contraction Theory [PDF]

Modeling, Identification and Control, 2010
This paper introduces a methodology for differential nonlinear stability analysis using contraction theory (Lohmiller and Slotine, 1998). The methodology includes four distinct steps: the descriptions of two systems to be compared (the plant and the ...
J. Jouffroy, T.I. Fossen
doaj   +1 more source

Incremental Accelerated Kernel Discriminant Analysis [PDF]

Proceedings of the 25th ACM international conference on Multimedia, 2017
In this paper a novel incremental dimensionality reduction (DR) technique called incremental accelerated kernel discriminant analysis (IAKDA) is proposed. Consisting of the eigenvalue decomposition of a relatively small-size matrix and the recursive block Cholesky factorization of the kernel matrix, a nonlinear DR transformation is efficiently computed
Gkalelis, Nikolaos, Mezaris, Vasileios
openaire   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

A subspace type incremental two-dimensional principal component analysis algorithm

Journal of Algorithms & Computational Technology, 2020
Principal component analysis (PCA) has been a powerful tool for high-dimensional data analysis. It is usually redesigned to the incremental PCA algorithm for processing streaming data. In this paper, we propose a subspace type incremental two-dimensional
Xiaowei Zhang, Zhongming Teng
doaj   +1 more source